Analytical Techniques

Clearest image of Ebola virus protein gained by researchers

18 October 2018 | By Drug Target Review

Researchers collaborated to identify the clearest image of the Ebola virus protein ever obtained using a cryo-electron microscope...

RNA molecule nc886 could unlock innate immunity

15 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified that the RNA molecule nc886 begins a series of events that leads to the destruction of viruses...

Elrig 2018: Drug discovery using small and large molecules

9 October 2018 | By Iqra Farooq (Drug Target Review)

The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...

NIH to build cell atlas of the human body

28 September 2018 | By Iqra Farooq (Drug Target Review)

The NIH's Common Fund programme looks towards building a cell map of all individual cells in the human body to aid the detection of disease...

Agilent Technologies

Mass spectrometry and drug development – how the two come together

22 September 2018 | By Manfred Raida (National University of Singapore)

Since the development of the so-called soft ionisation techniques: electrospray ionisation and matrix-assisted laser desorption and ionisation in the 1980s and early 1990s and the development of high-resolution mass spectrometers, mass spectrometry (MS) has come to the fore in studying complex biological systems...

Np63a should be targeted in squamous cell carcinomas

19 September 2018 | By Iqra Farooq (Drug Target Review)

A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...

Six compounds identified from 70,000 to help eradicate malaria

18 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...

Enhanced 3D neuron imaging could diagnose brain disease

13 September 2018 | By Drug Target Review

Researchers have combined an open source software programme and commercially available hardware to image neuron activity at high resolution...

Transparent high-resolution EEG array allows brain imaging

7 September 2018 | By Drug Target Review

Researchers have developed a see-through, dual-layered, mesh EEG device which is capable of measuring the electrical activity of individual neurons...

Nuclear PET imaging method developed for tumour detection

6 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers have developed a PET imaging method suitable for many forms of cancer, with high contrast and less inconvenience to patients...

New assay to detect genetic abnormalities in sarcomas

22 August 2018 | By Dr Zara Kassam (Drug Target Review)

A new study describes an assay, anchored multiplex PCR (AMP)-based targeted next-generation-sequencing (NGS), with superior diagnostic utility compared to conventional techniques...

Mouse models’ mimic lung disease

20 August 2018 | By Drug Target Review

Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...

Genes increasing the risk of triple-negative breast cancer identified

8 August 2018 | By Drug Target Review

Germ line genetic testing analyses blood samples and evaluates inherited genetic changes that increase the risk of certain cancers in an individual...

Aortic plaques may contribute to liver disease progression

3 August 2018 | By Drug Target Review

Aortic atherosclerotic plaque inflammation may contribute to the progression of non-alcoholic fatty liver disease to liver fibrosis...