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Biopharmaceuticals

Antibodies, immunoglobulin Ig proteins 3D medical image.

news

Refeyn launches software platform to automate mass photometry workflows

13 December 2024 | By Drug Target Review

Refeyn's new software automates mass photometry workflows, delivering faster and more consistent results for bioanalytical applications.

Scientists in lab coat working with test tubes

article

Toxicology transformed: Why accuracy now leads the way

11 December 2024 | By Bhupesh D. Sompura – Method Development Team Lead at Sannova Analytical

Regulatory changes are reshaping toxicology, with precision now at the forefront. We explore how accurate target analysis is transforming drug development, particularly for biotherapeutics.

3D protein molecules structure formed by amino acids and peptides.

article

Women pioneering change in biotech and protein production

10 December 2024 | By Alexandra Bonnyman

Alex Bonnyman is transforming protein manufacturing while championing women in STEM. Explore her journey of innovation, resilience, and inclusivity in biotechnology.

Chain of amino acid or bio molecules called protein - 3d illustration

article

Nobel Prize celebrates AI’s role in protein structure innovation

9 December 2024 | By Roberta Sher

The 2024 Nobel Prize in Chemistry honours AI's transformative impact on protein science, with breakthroughs set to reshape drug development.

news

Halozyme’s €2 billion bid to transform drug discovery

5 December 2024 | By Drug Target Review

By acquiring Evotec, Halozyme aims to enhance drug discovery and delivery, driving substantial growth in the pharmaceutical sector.

news

New CAR-T therapy shows promise in leukaemia treatment

1 December 2024 | By Drug Target Review

Obecabtagene autoleucel (obe-cel) has demonstrated strong efficacy in treating relapsed B-cell leukemia, with high response rates and minimal side effects.

An image to show human respiratory system and lungs anatomy

news

Breakthrough trial offers new hope for cystic fibrosis patients

28 November 2024 | By Drug Target Review

A promising new inhaled therapy is progressing in Phase 2 trials, presenting new opportunities for improving cystic fibrosis treatment.

Blood-brain barrier (BBB) in the human brain - closeup view 3d illustration

news

Blood-brain barrier breakthrough for ALS and Alzheimer’s disease

27 November 2024 | By Drug Target Review

A new blood-brain barrier-crossing platform enables the delivery of therapeutic molecules to the brain, offering potential treatments for ALS and Alzheimer’s disease.

article

Biotech leader champions targeted cancer treatments and diversity

25 November 2024 | By Dr Catherine Pickering (iOnctura), Drug Target Review

Driven by a passion for innovation and inclusivity, Dr Catherine Pickering, CEO of iOnctura, is on a mission to transform cancer treatment while championing diversity within the biotech industry.

whitepaper

Poster: Assays for DDX3, DDX5, DDX17, RIG-I, and MDA5

10 May 2024 | By BellBrook Labs

A panel of HTS assays was developed using the Transcreener platform to accelerate the development of selective helicase inhibitors.

whitepaper

Poster: Assays for PRMT5, MLL4, METTL3/14, & NSP14

7 May 2024 | By BellBrook Labs

AptaFluor SAH: A Homogenous, Universal Assay for Histone, RNA, & DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, & NSP14

whitepaper

A Guide to Measuring Drug-Target Residence Times

7 February 2024 | By BellBrook Labs

This guide provides technical background on concepts and techniques for use of Transcreener biochemical assays to measure drug-target residence times.

whitepaper

Whitepaper: Targeting kinases in the innate immune response

24 January 2024 | By BellBrook Labs

The guide provides examples of how Transcreener allowed rapid assay development to enable screening for kinases in innate immune pathways.

whitepaper

Case Study: Target discovery for rheumatoid arthritis

19 January 2024 | By Euretos

Learn more about Euretos computational disease model and how it predicts many of the known drug targets for RA.

article

A Guide to DNA Damage Response and Innate Immunity

10 January 2024 | By BellBrook Labs

In this guide, we provide an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets.

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Biopharmaceuticals