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Scientists uncover the role of PRMT5 in the production of myelin-forming cells
The discovery is a major step toward understanding the mechanisms of myelin production and the potential for treating certain central nervous system diseases...
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Cell Regeneration
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Alpha-synuclein clumps promote Parkinson’s progression
Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...
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EMT activation in tissue growth is also at play in cancer metastasis
Scientists in the USA have added a new dimension to the understanding of how cells alter their communication with one another by means of epithelial mesenchymal transition (EMT) during development, wound healing, and the spread of cancer.
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Stem Cells In-Depth Focus 2018
In this issue: urine-derived stem cells offer an innovative platform for drug testing and disease modelling, a paradigm shift in translational stem cell research, and the role of biomaterials in stem cell-based regenerative medicine.
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Microglia in the retina can spontaneously regenerate
NIH discovery in mice could lead to therapies to reduce vision loss from diseases of the retina...
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Scientists identify new stem cell that helps regenerate lung tissue after trauma
Researchers from the University of Pennsylvania have identified a lung stem cell that repairs the organ's gas exchange compartment, providing potential new approach to treat lung disease.
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Heart-muscle patches improve heart attack recovery
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals the patches significantly improved recovery from heart attack injury...
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Scientists discover a small molecule that halts kidney disease progression
A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.
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Scientists visualise structure of key DNA repair component
The ATR protein has been imaged at ‘near-atomic resolution’, providing greater insight into its activation in DNA repair.
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SBP scientists uncover mechanism for blood vessel regeneration
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.
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The immune system promotes spontaneous heart regeneration
In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.
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Pathways leading to beta cell division identified, may aid diabetes treatment
Pancreatic beta cells help maintain normal blood glucose levels by producing the hormone insulin -- the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes.
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Plasticell and Kings College London to collaborate in trials of blood platelet substitute
Over 10 million units of platelets are transfused worldwide each year in one of the most common procedures in clinical medicine. However, platelets derived from human donors can transmit infections and trigger serious immune reactions that eventually render the therapy ineffective (a condition known as alloimmune refractoriness). In addition, since…
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Plasticell to produce red blood cell substitute from pluripotent stem cells
Over 90 million blood transfusions are carried out worldwide each year and alternative sources to donor-derived blood are being sought to meet rising demand. In addition there is a need to secure a safer supply of blood products, chiefly in developing countries where there is a relatively higher risk of…
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Regenerating bone and cartilage tissues from apple waste
Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to ageing.
