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In this issue: urine-derived stem cells offer an innovative platform for drug testing and disease modelling, a paradigm shift in translational stem cell research, and the role of biomaterials in stem cell-based regenerative medicine.
NIH discovery in mice could lead to therapies to reduce vision loss from diseases of the retina...
Researchers from the University of Pennsylvania have identified a lung stem cell that repairs the organ's gas exchange compartment, providing potential new approach to treat lung disease.
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals the patches significantly improved recovery from heart attack injury...
A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.
The ATR protein has been imaged at ‘near-atomic resolution’, providing greater insight into its activation in DNA repair.
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.
In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.
Pancreatic beta cells help maintain normal blood glucose levels by producing the hormone insulin -- the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes.
Over 10 million units of platelets are transfused worldwide each year in one of the most common procedures in clinical medicine. However, platelets derived from human donors can transmit infections and trigger serious immune reactions that eventually render the therapy ineffective (a condition known as alloimmune refractoriness). In addition, since…
Over 90 million blood transfusions are carried out worldwide each year and alternative sources to donor-derived blood are being sought to meet rising demand. In addition there is a need to secure a safer supply of blood products, chiefly in developing countries where there is a relatively higher risk of…
Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to ageing.
19 October 2016 | By Niamh Louise Marriott, Digital Content Producer
A better understanding of how we could manipulate immune system conditions might aid to develop novel therapies against Alzheimer's, Kizil argues...
31 August 2016 | By Niamh Louise Marriott, Digital Content Producer
Using a mouse model, the rate of miscarriage was over 20% in the group that was not transplanted with EPCs while the miscarriage rate was only 5% in...
8 August 2016 | By Instituto Gulbenkian de Ciência
Researchers from the Instituto Gulbenkian de Ciência, Portugal, have discovered that the key controller of trunk, tail and spinal development is the Oct4 gene, one of the essential regulators of stem cells. The team intend to use their data to open new avenues to the study of spinal cord regeneration...
