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New class of drugs could help tackle treatment-resistant cancers
Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...
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Clinical Trials
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Stem cell therapy discovery for age-related macular degeneration
Stem cell-derived retinal cells need primary cilia to support the survival of light-sensing photoreceptors...
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IONIS-HTTRx lowers deadly Huntington’s disease protein
The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial…
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Meeting access challenges with adaptive trial designs
With access challenges even after successful but costly development programmes, the industry is under pressure to speed up the clinical development process and produce more for less. Adaptive trial designs, more collaborative working and data sharing could provide a solution in the area of cancer immunotherapy, says Jacqueline Karmel, principal…
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ARBs may solve the global antibiotic crisis by 2020
A British biopharmaceuticals company, have developed Antibiotic Resistance Breakers which can restore the original potency against both Gram-positive and Gram-negative bacteria...
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Scientists identify new treatment for Activated PI3-kinase Delta Syndrome
Scientists have identified a new treatment approach for patients with a rare inherited immune disorder...
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Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
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CRISPR-engineered cancer model to test therapeutics
A new technique for modelling leukaemia may aid drug discovery...
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Three-in-one antibody may protect from HIV-like virus
A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...
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Therapy proves effective in subgroup of COPD patients
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...
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DNA sequencing could open up new drug indications for rare cancers
A network of hospitals have systematically collected biopsies from metastatic cancer patients in order to create a global database...
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Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
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Novel immuno-oncology treatment for patients with advanced solid tumours
An experimental immuno-oncology treatment will move into early phase clinical trials for patients with advanced solid tumours...
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Promising therapeutic approach for improving mitochondrial function
Scientists have made progress in the development of products that improve mitochondrial function...
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Biological bypass shows promise in coronary artery disease
A new gene therapy that targets the heart and requires only one treatment session has been found safe for patients with coronary artery disease...
