Specialised proteins could halt cytokine storms in COVID-19 patients
Researchers who developed modified proteins say this could be used in the fight against COVID-19, by tackling cytokine storms.
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Researchers who developed modified proteins say this could be used in the fight against COVID-19, by tackling cytokine storms.
Researchers have created a new kind of immunotherapy using the interleukin-27 (IL-27) cytokine to effectively combat tumours in vitro and in vivo.
Many cell lines require the addition of specific growth factors to their culture media even if the media contains serum.
Researchers have identified that in leukaemia, mutated receptors allow blood stem cells to activate one another without the proper signal and suggest this discovery could lead to targeted novel therapies.
Researchers reveal importance of IL-15 in T cell autophagy in the liver, presenting a potential strategy to enhance immunotherapies.
Immune cell therapies, stem cell therapies, and regenerative medicine, often grouped into the category of advanced therapy medicinal products (ATMPs), offer some of the most revolutionary and exciting new approaches for treating human disease.
Researchers have found that MAIT immune cells respond rapidly to group A streptococcal infection, causing inflammation and toxic shock, which presents a therapeutic target.
Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…
Modern cell biology requires a wide variety of applications to keep up with the numerous exciting directions that research takes us. Detection technologies ranging from fluorescence to cellular imaging have become common in today’s laboratories.
Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
CD4+ T-cells play a central role in directing adaptive immune responses against invading microbial pathogens.
17 January 2019 | By IntelliCyt, a Sartorius Company
Multiplexed approach to measure T-cell activation, proliferation and quantify cytokine release in a single well
Cell therapies offer revolutionary new approaches for treating humandisease. Most of these treatments use GMP cytokines and growthfactors for the differentiation, expansion, and maintenance of cells.It is critical that GMP protein suppliers offer the optimal combinationof consistency, safety, and stable supply chain.
Growing evidence reveals that using single immunotherapies to treat oncological disorders may lead to cancer-killing T-cell overdrive,initiating life-threatening autoimmune reactions including cytokinestorm; also known as hypercytokinemia or Cytokine Release Syndrome(CRS). Recently, checkpoint blockade using anti-programmed cell death1 (anti-PD-1) inhibitors became a prevalent approach for stimulatinganti-tumour immune system.
Researchers have identified a new gene that plays a critical role in regulating the body's immune response to infection and disease...