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UBR5 protein may reduce neurodegeneration in Huntington’s disease
Scientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease...
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Disease Research
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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BCX7353 shows hope for hereditary angioedema
A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...
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Blood test predicts the best treatment for prostrate cancer
The study showed that patients testing positive for AR-V7 responded better to taxane-based chemotherapy and negative to hormone-targeted therapy...
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Researchers identify new arthritis severity gene
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by...
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Study suggests viral connection to Alzheimer’s disease
A first-of-its-kind study implicates another culprit in the path to Alzheimer's disease: the presence of viruses in the brain...
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Promising drug targets for t-cell lymphoblastic leukaemia
Silencing the gene behind the production of HSP90, a target in the HSF1 pathway, effectively kills leukaemia cells, without affecting healthy cells...
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Adapting drug discovery to Artificial Intelligence
Drug discovery has always been challenging; today, more so than ever. While there has been success in addressing many diseases, others remain intractable...
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How cannabis and cannabis-based drugs can harm your brain
Long-term use of either cannabis or cannabis-based drugs impairs memory...
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Recessive disorder impairing eyesight has been discovered
Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...
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P2X4 receptor key for delaying the progression of Multiple Sclerosis
Researchers have identified a receptor in the microglial cells that increases their anti-inflammatory potential in order to reduce the damage in MS...
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32,000 images of analysed CT scans released for AI development
Thousands of images have been released to encourage scientists to develop their analysis of lesions, advocating its use for the development of a new universal lesion detector...
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Aggressive Th17 cells aggravate Parkinson’s disease
Researchers identify Parkinson's disease as a possible autoimmune disease...
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Breath tests could detect pancreatic cancer
Breath tests analysing organic compounds in exhaled breath could be used as a new diagnostic tool for pancreatic cancer...
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From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research
Mesenchymal stem cells (MSCs) are fibroblast-like cells that give rise to mesenchymal derivatives including bone, fat and cartilage cells. In addition to the bone marrow, they can be readily obtained from adult vascularised peripheral tissues including adipose, olfactory, respiratory tissue, and peripheral blood.
