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Article: Linking genomics with proteomics to accelerate the search for drug targets
Several recent studies highlight the promise of combining genomics and proteomics to uncover new, robust drug targets.
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Disease Research
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Novel technique provides detailed map of lung pathology in COVID-19
Researchers have used imaging mass cytometry to analyse the cellular landscape of diseased lung tissue in severe COVID-19, revealing insights into the disease.
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Application note: Metagenomic analysis of the microbiome with MagMAX
The isolation of microbial DNA is a key prerequisite for determining the microbiome profile of each body habitat.
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Scientists find evidence that SARS-CoV-2 infects cells in mouth
Researchers have shown that SARS-CoV-2 infects mouth cells, which could inform the development of treatments against the oral symptoms of COVID-19.
podcasts
Episode 1 – Dr Sri Gopal, Janssen Pharmaceuticals
Listen along to learn more about drug development for schizophrenia from Dr Sri Gopal, Head of Psychiatry R&D for Janssen!
article
Identifying a novel treatment for heart attacks
Professor David Merryman explains how his team targeted the serotonin 2B receptor in animal models to preserve cardiac function six weeks after a heart attack.
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Whitepaper: Simple Western™ produces publication-ready results
Simple Western™ is an automated capillary immunoassay that produces publication-ready data to meet the highest standards of data integrity and rigor.
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Lung-on-a-chip models enable advanced study of immune response
Researchers have reviewed lung-on-a-chip technologies, finding they are useful for representing the various disease pathologies.
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Catalogue: Cell isolation with Dynabeads
Magnetic separation with Dynabeads helps ensure that the isolated cells are not affected by passage through a dense column.
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Infographic: Proteogenomics strategies
Why you should link genomics with proteomics to accelerate the search for effective drug targets.
news
Molecular technique could provide key for SARS-CoV-2 drug discovery
Researchers are using a new method to isolate the complex between SARS-CoV-2 and the ACE2 receptor to keep it embedded in the cell membrane.
article
SARS-CoV-2 variants: the role of sequencing and vaccine development
Professor Martin Michaelis and Dr Mark Wass explain why new SARS-CoV-2 variants are emerging around the world and how vaccines will have to adapt in response.
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Catalogue: Nuclease-Free tubes, tips & buffers
Working with RNA requires rigorous nuclease contamination controls in place. Stock up on Nuclease-Free tubes tips and buffers #Back2Lab
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Spike protein analysis explains faster spread of SARS-CoV-2 variants
Using cryo-electron microscopy, researchers have imaged how the SARS-CoV-2 Spike protein changes with the D614G mutation to enable faster spread of infection.
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Researchers develop model of early human embryo from skin cells
Scientists have created the first model of early human embryos by reprogramming fibroblasts into a blastocyst-like structures.
