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Novel therapeutic approach shows promise in mice with COPD
By blocking the lymphotoxin beta receptor signalling pathway, researchers were able to prevent COPD progression and induce a full restoration of lung tissue.
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Persistence of infected cells in lungs could explain long-term COVID-19 symptoms, say scientists
Researchers have found the genome of COVID-19 and infected cell syncytia in the respiratory cells of deceased patients, potentially explaining long-term coronavirus effects.
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Age may be a primary determinant of melanoma treatment resistance
Scientists have shown that age may cause genetically identical melanoma skin cancer cells to respond differently to treatment, making age a primary factor in treatment response.
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Autoantibodies and over-active neutrophils may be cause of COVID-19 blood clots
According to a new study, blood clots in patients with severe COVID-19 are caused by an autoimmune antibody that circulates in the blood and attacks cells.
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Researchers reveal how allergens may trigger itching
Certain sensory neurons and Substance P are potential drug targets for the development of novel allergy preventions or treatments, according to scientists.
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SARS-CoV-2 can disrupt the blood-brain barrier, find scientists
Binding of SARS-CoV-2 spike proteins to the brain’s endothelial cells can cause the blood-brain barrier to become leaky, potentially causing the neurological symptoms associated with COVID-19.
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Researchers discover novel cancer immunosuppression mechanism
According to the study, the transcription factor IRF4 drives T cell differentiation and immunosuppression in multiple human cancers.
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Lysosomes key to coronavirus shedding, finds study
Scientists reveal that coronaviruses de-activate lysosomes before using them to exit infected cells and spread through the body.
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Leveraging flow cytometry to explore COVID-19 immune responses
Researchers used flow cytometry to characterise which types of T cells are involved in the immune response to COVID-19 and what they target.
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Cellular senescence as a drug target
New research reveals that age-related declines in cellular function and proliferation occur in multiple stages, accompanied by different inflammatory responses.
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ebook: Phenotypic screening with iPSC-derived cardiomyocytes and neurons
Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
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Analysis of mouse neuroinflammation samples aided by flow cytometry
A new study has highlighted the advantages of using flow cytometry for the analysis of neuroimmune cell populations from mouse models.
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New imaging method reveals glycan vaccine targets on HIV molecules
Using cryo-electron microscopy and site-specific mass spectrometry, researchers have mapped the glycans that shield HIV from the immune system.
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ebook: Eliminate 50/60 Hz line-frequency noise in less than one second
A major challenge within electrophysiology labs is 50 or 60 Hz line frequency electrical noise, which can either distort or completely drown out biological signal.
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On-demand webinar: Complete workflow solution from gene-to-protein
23 October 2020 | By
Our full gene-to-protein workflow can support your research for rapid protein production early during drug development so you can minimize changes from R&D to bioproduction.
