news
Scientists develop promising new gonorrhoea antibiotic
The drug candidate, JSF-2659, has been developed to be administered orally, and could be a game changer in treating gonorrhoea.
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Drug Development
news
New research finds cancer-associated fibroblasts can promote or inhibit drug sensitivity
Researchers found that fibroblasts had varying effects on tumour cells based on both the type of non-small cell lung cancer and the drug used for treatment.
news
Novel streamlined screening method could discover new horizons in chemical reaction design
An in-silico reaction screening strategy could produce compounds potentially useful for novel drug development.
article
The hunt for new hepatitis treatments
In this exclusive interview for World Hepatitis Day with Drug Target Review, Professor Ziv Ben Ari from the Sheba Medical Center discusses recent progress towards hepatitis treatment.
news
New discovery in cancer progression paves way to combat the disease
Researchers have identified an important gene that could enable more targeted treatment for cancer.
news
Chicken eggs used to produce SARS-CoV-2 antibodies
Researchers in the US have found that antibodies to the SARS-CoV-2 Spike protein can be produced in hen eggs.
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How the innate immune system detects HIV-1
Researchers have found that the innate immune system requires two steps to defend against HIV-1, even when the virus is present in small amounts.
news
How EGF receptors influence cell growth
A new insight into the way the EGF receptor sends signals into cells could help researchers design new cancer drugs that target this protein.
webinar
Comprehensive in vitro approach to evaluate transporter-mediated drug interactions in drug discovery
4 July 2022 | By Eurofins Discovery
In this on-demand webinar, an assay strategy to assess transport-mediated drug interactions that complies with regulations is examined.
news
New effective combination therapy for paediatric T-acute leukaemia
The combination of two drugs was more effective in eradicating leukaemia cells in zebrafish and human disease than using a single drug.
news
A mathematical algorithm to network complex drug interactions
Researchers used mice to develop a mathematical algorithm of a heart attack.
article
The promise of cell therapy: scaling up a new treatment paradigm for hearing loss
Expectations are growing worldwide for discoveries that will harness the potential of cell therapy, which has already brought breakthroughs in therapeutic areas where there is an unmet need, from oncology to ophthalmology and rare disease. In this article, Dr Terri Gaskell, Chief Technology Officer at Rinri Therapeutics, explores some of…
article
Challenges and opportunities: lessons learned in developing potential gene therapy cures
While the full potential of gene therapies continues to be realised, their successes in rare diseases promote them as a promising treatment modality. Dr Gaurav Shah, Chief Executive Officer of Rocket Pharmaceuticals discusses the future of gene therapies as well as the company’s progress in in vivo and ex vivo programmes.
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Leveraging a dual technology platform to develop gene therapies for a range of rare diseases
In this article, Dr Mary Spellman, Chief Medical Officer and Senior Vice President of R&D at Castle Creek Biosciences, discusses how a versatile dual platform of ex vivo and in vivo gene therapy technologies is being utilised for the development of novel gene therapies for a broad range of rare…
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Drug Target Review Cell & Gene Therapy ebook
This ebook features articles from gene therapy specialists that look at current platforms as well as the future of promising modalities for gene therapies. It also tackles novel stem cell technology considerations and gives insight into the careful balancing act between efficacy and safety in gene therapy.
