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Drug Development

 

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Development by design methodology: the key to successful manufacturing of patient-specific cell therapies

11 July 2017 | By ,

Recognised as the next wave of medicine, cell therapies have made significant strides over the last several years. But such advancements can present unique challenges, especially as more products move out of the clinic and toward commercialisation. And unlike typical pharmaceuticals, cell therapies rely heavily on the manufacturing process to…

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New research highlights key differences between mice and men

4 July 2017 | By

Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.

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Targets In-Depth Focus 2017

5 June 2017 | By

Included in this Targets In-Depth Focus: Intracellular target validation in cellular systems; New drug targets identified to defend against chlamydia infections using CRISPR and stem cells; Novel solutions for tough targets with real bite...

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Screening In-Depth Focus 2017

5 June 2017 | By

Included in this Screening In-Depth Focus: Phenotypic and target-based screening; Killing cancer cells using clinical drug resistance; Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool...