Drug Discovery

Possible treatment discovered for severe dengue disease

28 August 2019 | By Rachael Harper (Drug Target Review)

New findings suggest a possible new treatment strategy for severe dengue disease using the tryptase inhibitor, nafamostat mesylate.

Osteoporosis in mice reversed with new drug target

21 August 2019 | By Rachael Harper (Drug Target Review)

A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.

Key mechanism in tuberculosis survival discovered

19 August 2019 | By Victoria Rees (Drug Target Review)

A new study has revealed that M. tuberculosis uses a unique type of antacid which gives immune cells indigestion, enabling the bacteria to survive.

Beyond the phenotype: using AI to better understand disease

19 August 2019 | By Victoria Rees (Drug Target Review)

Claus Bendtsen at AstraZeneca reveals how AI can be used to improve our understanding of disease, to help identify the causes of conditions and aid in drug discovery.

Fruit fly model for studying uric acid diseases developed

16 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have created a fruit fly model to investigate uric acid-related diseases such as diabetes to aid in drug development.

Applying AI language translation to the creation of new pharmaceuticals

16 August 2019 | By Dr Sam Genway

Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.

Blood-brain barrier role in Alzheimer’s patients revealed by tissue model

13 August 2019 | By Rachael Harper (Drug Target Review)

A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.

New drug could be used for targeted cancer therapies

7 August 2019 | By Rachael Harper (Drug Target Review)

A new drug called IP1867B, which could be used for future treatments of brain tumours, is being examined.

New therapy discovered to treat acute lymphoblastic leukaemia

30 July 2019 | By Drug Target Review

Researchers have discovered a new combination therapy to treat drug-resistant acute lymphoblastic leukaemia, tested in pre-clinical trials.

Encouraging drug discovery and therapeutic targets for dementia

26 July 2019 | By Victoria Rees (Drug Target Review)

A review has been published by experts in neurodegeneration research, detailing six ways to improve dementia research. This article investigates one of these suggestions, focusing on how we can improve drug target identification.

Promising drug developed for ovarian and pancreatic cancers

22 July 2019 | By Drug Target Review

An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.

Crystals mapped to advance treatments for stroke, diabetes and dementia

5 July 2019 | By Drug Target Review

Researchers haved mapped the crystal structure of a protein to find out how a drug latches onto it.

Titian Software Ltd

Artificial intelligence in the world of drug discovery

4 July 2019 | By Victoria Rees (Drug Target Review)

Charlotte Walker-Osborn, a Partner and Head of Technology Sector (International) at global law-firm Eversheds Sutherland and a legal expert in technology law, explains some of the challenges and potential future of artificial intelligence (AI) in the field of drug discovery.

Study reveals vulnerability of common pathogenic viruses

13 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have developed a stabilisation technique for widespread viruses, creating drug opportunity.