news
D-PDMP reverses hair loss and skin damage linked to fatty diet
In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...
List view / Grid view
Mass Spectrometry
news
Breath tests could detect pancreatic cancer
Breath tests analysing organic compounds in exhaled breath could be used as a new diagnostic tool for pancreatic cancer...
news
New target for treating heart failure identified by Penn Medicine researchers
Reversing modifications in diseased heart muscle cell struts called microtubules (MT) can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
article
Could fingerprints play a role in drug trials of the future? A forensic scientist’s perspective
Although readers of Drug Target Review may be more focused upstream of clinical trials in the drug discovery pipeline, the efficacy of clinical trials should also be of interest. Millions of pounds invested in drug discovery in the laboratory could easily go to waste if the clinical trials stage is…
news
13th International Conference on Metabolomics and Systems Biology
Euro Metabolomics 2018 will be a platform to investigate on recent research and advancements that can be useful to the researchers.
news
Charles River Laboratories expands services for early discovery screening
Addition of high-throughput technologies and expanded pharmacokinetic services enhances existing support for small molecule drug discovery.
news
Researchers uncover up to 100 potential drug targets for cancer
In a new study based on mouse cells, researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.
news
ELRIG UK hosts inaugural Discovery Technologies event
ELRIG (European Laboratory Research & Innovation Group) has announced its first Discovery Technologies meeting, which will take place at Alderley Park, located near Macclesfield in Cheshire.
news
New study discovers cancer-relevant protein shield
Researchers have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment...
article
How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
news
LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
news
GalNAc-T6 enzyme selectively up-regulated in colon adenocarcinomas
Researchers have identified an enzyme that appears to drive the conversion of normal colon tissue into cancer...
news
Charles River announces success of integrated discovery project with ENYO Pharma
Capture compound mass spectrometry technology enables target identification...
news
Richard Goodwin joins DTR Advisory Board
Dr Goodwin is the latest top-level scientist to join DTR's advisory board
article
Mass spectrometry imaging in drug discovery
Mass spectrometry imaging allows direct measurement of the molecular composition of a sample. It can be used to image the spatial distribution of exogenous drugs and endogenous metabolites simultaneously over the surface of tissue sections or small biopsy, allowing new insights into both compound efficacy and safety during drug discovery.
