Protein

Direct toxic action of beta-amyloid in Alzheimer’s patients identified

12 August 2019 | By Rachael Harper (Drug Target Review)

The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.

Therapeutic target for Kennedy’s disease and prostate cancer proposed

9 August 2019 | By Rachael Harper (Drug Target Review)

A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.

Potential treatment target identified for Crohn’s disease

9 August 2019 | By Rachael Harper (Drug Target Review)

Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.

Researchers grow genetically engineered mini livers to study disease

6 August 2019 | By Rachael Harper (Drug Target Review)

The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.

Experimental treatment slows prion disease

5 August 2019 | By Rachael Harper (Drug Target Review)

A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice

Protective protein guards against DNA damage

5 August 2019 | By Rachael Harper (Drug Target Review)

It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.

Antibody therapy extends survival in mice with pancreatic cancer

1 August 2019 | By Rachael Harper (Drug Target Review)

Scientists have found a way to target and knock out a protein which is widely involved in pancreatic cancer cell growth, survival and invasion.

Cancer cell nutrient pathway mechanism discovered

1 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.

Newly discovered signal could lead to anti-cancer therapies

31 July 2019 | By Drug Target Review

Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.

New discovery could lead to new treatments for Parkinson’s

30 July 2019 | By Drug Target Review

New discovery makes it possible to design new therapies to replace alpha-synuclein's function in people with Parkinson's disease.

Enzo Life Sciences

Scientists control living cells using artificial protein switch

24 July 2019 | By Drug Target Review

Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.

Promising drug developed for ovarian and pancreatic cancers

22 July 2019 | By Drug Target Review

An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.

Transfer of oncogene in colon cancer cells demonstrated

22 July 2019 | By Drug Target Review

A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.

Whitepaper: Neural Cell Culturing Guide

22 July 2019 | By Bio-Techne

The advent of in vitro culturing of neural cells has been central to driving our understanding of the nervous system.