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Protein can slow intestinal tumour growth
A new mechanism for regulating stem cells in the intestine of fruit flies has been discovered by researchers at Stockholm University.
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Psoriasis treated with compound derived from immune cells
A compound may be effective against other autoimmune diseases, mouse study shows...
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New study discovers cancer-relevant protein shield
Researchers have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment...
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Blood test may predict future risk of cardiovascular events
A study of 27,000 women finds that branched-chain amino acid levels in the bloodstream are as predictive of heart disease as LDL cholesterol, other risk factors...
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Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking
In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.
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Cryo-electron microscopy reveals structure of a herpesvirus capsid
Researchers have reconstructed the 3.1 Å structure of the herpes simplex virus type 2 (HSV-2) B-capsid and built the atomic model, thus expanding the understanding of the assembly mechanism of the capsid...
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
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Study reveals a way to make prostate cancer cells run out of energy and die
Scientists have discovered that cells lacking the tumour-suppressor protein PTEN – a feature of many cancers – are particularly vulnerable to drugs that impair their energy-producing mitochondria.
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SAMHD1 enzyme may block HIV disease progression
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works...
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IPSE protein has potential to alleviate debilitating disease
Chemotherapy-induced hemorrhagic cystitis alleviated by a protein that parasites use to keep hosts alive...
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Study changes long-held concepts of cell decoding
NIH scientists discover macromolecular complexes that could enable medication development...
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KIF5A gene associated with the development of ALS
An international team of researchers has identified a new gene associated with the development of amyotrophic lateral sclerosis...
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MVP found to be consequential in 16p11.2 deletion syndrome
Neuroscientists have identified a specific molecular mechanism that appears to undermine the ability of neurons to properly incorporate changes driven by experience...
whitepaper
Application note: Simultaneous dual phosphoprotein target analysis with Alpha Terbium SureFire Ultra Multiplex
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
