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Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
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T cells
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Synthetic T-cells engineered to combat cancer
Researchers have engineered T-cells in the laboratory to combat tumours...
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DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
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Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
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Researchers find switch that turns on immune cells tumour-killing ability
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
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Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
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Killer peptide helps eliminate resistant cancer cells
Scientists have identified a Par-4 amino-terminal fragment that is released by diverse therapy-sensitive cancer cells...
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New gene mutations found in white blood cells in rheumatoid arthritis patients
Finnish researchers have found that an accumulation of gene mutations, similar to those typically seen in the development of cancer, also occur in some patients with rheumatoid arthritis.
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Scientists uncover how sunlight on skin reduces eczema inflammation
A new study has identified how exposure to sunlight alleviates symptoms of eczema by triggering the release of a compound in the skin that dampens inflammation.
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Blood cell discovery identifies patients with aggressive prostate cancer
Patients who have aggressive prostate cancer could be identified by a highly accurate and simple blood test, according to a new study.
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Faulty immune cells may play role in alopecia and baldness
The new study suggests that defects in Tregs could be responsible for alopecia areata, a common autoimmune disorder that causes hair loss, and could potentially play a role in other forms of baldness, including male pattern baldness
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Scientists light the way for immune system to attack cancer
The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumours.
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Cancer-causing virus masters cell’s replication & immortality
Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated 9/10 humans without causing any ill effects. That is, until this virus causes mononucleosis…
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A new role for an old immune cell may lead to novel therapies
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
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Amgen and Immatics to collaborate on bispecific cancer immunotherapies
The collaboration will combine Immatics’ Xpresident target discovery and T-cell receptor (TCR) capabilities with Amgen’s validated Bispecific T-cell Engager (BiTE) technology with the aim of creating novel oncology drugs.
