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Neurons made from skin cells are valid when studying disease
A study has found that using skin cells and transforming them into neurons is a valid approach to study neurodegenerative diseases such as Parkinson's...
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Therapeutics
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Potential therapeutic target for ALS revealed
Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...
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Stopping inflammation using a molecular switch
A component in the ubiquitin system has been described as being able to deactivate the innante immune system and could help to prevent immune conditions...
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Engineered T-cells promote acceptance of organs after transplant
Controlling coronin 1 in T-cells could lead to the immune system not attacking transplanted organs, but still fighting other infections...
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Using the SVM method to predict enhancers from tissues and cell lines
A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.
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CRISPR repurposed to develop better antibiotics
Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
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UCLA researchers correct mutation causing IPEX
A stem cell therapy rectifying the FoxP3 gene has been developed to treat IPEX, and has virtually cleared symptoms of the condition in mice...
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Two-antibody cocktail could treat Ebola in one dose
A study has described a two-antibody cocktail medication that has been successful in vivo italics trials and could treat Ebola in one dose...
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Stem cell study optimises bone marrow transplants
A study has shown how stem cells that are transplanted act in a different way to those ordinarily present, without a transplant...
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Drug sponge could minimise effects of cancer therapy
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
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Insights into controlling gene expression
A study has given insight into gene expression and could enable scientists to determine how certain RNAP inhibitors work within the body...
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‘Activating’ the immune system against cancer
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
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Inhalable mRNA could treat lung disease
An inhalable mix of a polymer and mRNA molecules, used to produce luciferase, could be the method of treating lung diseases in the future...
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Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
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Triple-negative breast cancer could be treated using experimental treatment
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
