news
Osimertinib resistance explained by computer simulations
Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
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Therapeutics
news
PGEC-derived organoids produce stable gut and liver tissue
Researchers have bioengineered organs that are free from the risk of tumour growth--and of sufficient volume and size for viable transplant...
news
Scientists target glioma cancer stem cells which could improve patient survival
Dartmouth scientists have successfully uncovered a therapeutic approach that targets aggressive brain cancer stem cells and could lead to improved patient survival.
news
SMi’s 9th annual RNA Therapeutics conference will take place in just 2 weeks!
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
news
New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
news
Elimination of c-Raf kinase induces regression of advanced lung tumours
A study has shown how the elimination of the c-Raf kinase by genetic manipulation causes the regression of Kras oncogene-driven advanced lung tumours...
news
The highlights to look forward to at SMi Groups Controlled Release Delivery Conference in March 2018
Our agenda is packed with keynote addresses, expert speakers, informative content and senior figures from within the industry…read on to find out more…
news
Discovery into cells’ energy supply could lead to targeted cancer treatment
Scientists have made a significant breakthrough in understanding how the molecular machines that produce key proteins are cleaned and maintained. ..
news
APC-mimetic scaffolds could facilitate more effective precision immunotherapies
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
news
Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s
A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
news
X chromosome reactivation could treat Rett syndrome
Reactivation of the inactive X chromosome could lead to an increased expression of the healthy protein underlying the neurodevelopmental disorder...
news
Precision editing of gut bacteria used to treat colitis
Researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis...
whitepaper
Application note: LANCE Ultra TR-FRET – based detection and modulation of Phosphorylated STAT3 levels in human cells
In this application note, PerkinElmer demonstrates how LANCE® Ultra, a homogeneous assay format, can be used to quickly and accurately assess modulation of pSTAT3.
news
CXCR4 receptor provides therapeutic target for ovarian cancer
Researchers have described a key cellular receptor in the processes of metastasis in ovarian cancer, the findings may lead to the use of CXCR4 inhibitors as a therapeutic target...
webinar
High throughput flow cytometry for multifactorial evaluation of novel therapeutic candidates using an innovative In vitro immuno-oncology screening platform
4 January 2018 | By IntelliCyt Corporation
In this webinar, speakers discussed how the IntelliCyt iQue Screener Plus platform is being utilised to deliver rich datasets for compound screening, target validation and is how it is transforming immuno-oncology.
