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Therapeutics

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Declines in plasticity reveal promising targets for Alzheimer’s disease

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

Brain changes linked to memory loss may provide a new focus for exploring ways to treat or prevent dementia...

news

Self-regulating nanoparticles could treat cancer

24 October 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed 'intelligent' nanoparticles which heat up to a temperature high enough to kill cancerous cells...

news

N-alpha-acetyltransferase D found to promote lung cancer progression

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

NatD, which mediates N-alpha-terminal acetylation of histone H4, found to promote lung cancer progression...

news

Research reveals antibody treatment pathway for severe allergic asthma

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...

Integrated Drug Discovery Panel – Your questions answered!

webinar

Integrated drug discovery panel – your questions answered!

28 September 2017 | By Charles River

During this peer panel discussion, team members from Charles River discussed their views and strategies on Drug Discovery...

whitepaper

Whitepaper: Advancing therapeutic antibody discovery with multiplexed screening

28 September 2017 | By IntelliCyt Corporation

In this whitepaper, IntelliCyt Corporation describe how the iQue Screener is used to perform multiplexed screens for antibody binding to either cell surface or to circulating target antigens...

news

Blocking ApoE4 may prevent nerve cell death in Alzheimer’s disease

21 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified that the presence of ApoE4 exacerbates the brain damage caused by toxic tangles of tau protein...

news

B-cells promote melanoma progression and resistance to therapy

21 September 2017 | By Dr Zara Kassam (Drug Target Review)

Depletion of B cells in the tumour micro-environment shows anti-tumour activity in patients with advanced metastatic melanoma...

news

Potential new target for colon cancer

13 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have demonstrated that a novel protein can cause normal cells in the lining of the colon to become malignant, grow and spread...

news

Cell surface protein may offer target in treating childhood cancers

12 September 2017 | By Dr Zara Kassam (Drug Target Review)

Immunotherapy drug candidate could be potent weapon against neuroblastoma and other paediatric malignancies...

news

Therapy proves effective in subgroup of COPD patients

12 September 2017 | By Dr Zara Kassam (Drug Target Review)

An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...

news

Venomous compounds may lead to better skin treatments

11 September 2017 | By Dr Zara Kassam (Drug Target Review)

Compounds derived from fire ant venom can reduce skin thickening and inflammation in psoriasis...

news

Mechanism identified to be responsible for the growth of epithelial tumours

11 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers reveal the capacity of epithelial-derived tumours to grow in the absence of a microenvironment...

news

Blood tumour markers warn against the progression of lung cancer

7 September 2017 | By Dr Zara Kassam (Drug Target Review)

Cancers can secrete complex molecules into the blood, researchers have now begun to further define their potential...

news

New mindset in the search for stroke therapies

7 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a promising new avenue to explore in the search for stroke treatments...

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Therapeutics