whitepaper

Application note: Evaluation of different ion-pairing reagents for LC/UV and LC/MS analysis of oligonucleotides

Posted: 25 January 2021 | | 1 comment

The effect of various ion pairing reagents (amines and acidic counterions) on the LC/UV and LC/MS analysis of oligonucleotides (ONs) has been studied.

This application note shows that there are numerous variables available for optimisation of the analytical conditions for oligonucleotides.  The analyses were carried out on an Agilent 1290 Infinity II LC System with UV detection by DAD and an Agilent 6530 LC/Q-TOF.

    [dynamichidden sponsors "Agilent]

    To read this application note in full, please complete the form below:

     









    This specialist content is provided to you free-of-charge thanks to the kind support of Agilent. For full details of how they will treat your information please view their Privacy Policy.

    By clicking submit you confirm that you accept our terms and conditions and privacy policy.

    One response to “Application note: Evaluation of different ion-pairing reagents for LC/UV and LC/MS analysis of oligonucleotides”

    1. praveen paliwal says:

      I need this

    Leave a Reply

    Your email address will not be published. Required fields are marked *