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Cell confluency is a key parameter for all cell biologists as it is the beginning of all other cell culture experiment such as transfection, cell-based assays and cell culture quality control...
In this whitepaper, IntelliCyt Corporation describe how the iQue Screener is used to perform multiplexed screens for antibody binding to either cell surface or to circulating target antigens...
This application note illustrates the value of multiplexing, rapid sampling, and assay miniaturisation using QBeads on the iQue Screener...
In this application note, IntelliCyt Corporation demonstrate a fast, efficient, radioactivity-free CMC assay with low sample input requirements, enabling miniaturisation to 384-well plates, using the iQue® Screener...
In this application note IntelliCyt Corporation report on the development and validation of their family of MultiCyt QBeads for the detection of cytokines in a high-throughput screening application on the iQue Screener...
In this application note Thermo Fisher Scientific compare data from the KingFisher Flex and KingFisher Presto instruments. Our results clearly indicate that the instruments produce equivalent yields and quality of extracted products. DNA extraction from human whole blood is shown as an example...
In this application note, PerkinElmer discuss how their ValiScreen CXCR2 GPCR cell line (#ES-145-C) was utilised to examine the downstream effects of chemokine receptor modulation using multiple blocking antibodies and a small molecule...
Peer-reviewed paper on how touchscreen testing is a translational tool to assess cognitive function in a mouse model of Alzheimer’s disease...
Peer-reviewed publication on new strategies to target misfolded protein aggregates at various steps of protein production and processing...
In this application note, Sheraz Gul (Fraunhofer-IME SP), Markus Wolf (Fraunhofer-IME SP), Enda O’Connell (National University of Ireland Galway) and Howard Fearnhead (National University of Ireland Galway), demonstrate that the Echo 550 Liquid Handler can precisely and accurately transfer nanolitre volumes of compound with acoustic energy in a completely contact-free…
This technical note offers practical tips for facilitating the use of Thermo ScientificTM VarioskanTM LUX multimode reader and InvitrogenTM EVOSTM FL Auto Cell Imaging System with the goal of achieving successful cellular quantification and imaging of mammalian cells in microplate-based assays...
The Custom Assay Development (CAD) program at DiscoverX develops tailor-made cell lines optimised for your needs, enabling you to jump start your drug discovery programs...
IDEA Bio-Medical offers a new feature for spatial detection and characterisation of temporal kinetics of rare events using its advanced HCS system, WiScan® Hermes...
This application note demonstrates the feasibility of combining the Thermo Scientific™ Varioskan™ LUX multimode reader and Invitrogen™ EVOS™ FL Cell Imaging System for the fluorescence-based quantification and imaging of complex biological systems, without requiring separate assay optimisation...
Monitoring cellular drug permeability and target engagement enables assessment of compound efficacy and confirmation of mode of action. InCELL Pulse target engagement assays provide the ability to confirm compound cell entry and target engagement while overcoming limitations of current target engagement assays...
