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New potential strategy to combat Alzheimer’s disease
Researchers have revealed the molecular mechanism behind a rare mutation has been associated with numerous neurodegenerative diseases...
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Alzheimer’s disease
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Antibody targets create potential for a unified treatment approach
Antibody targets thought to cause the most damage in neurological disorders, creates potential for a unified treatment approach...
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Artificial intelligence predicts dementia before onset of symptoms
Scientists have used artificial intelligence techniques and big data to develop an algorithm capable of recognising the signatures of dementia two years before its onset, using a single amyloid PET scan...
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Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s
A collaboration between Prof Lucía Chávez-Gutiérrez and Prof Bart De Strooper of VIB-KU Leuven has revealed the molecular basis of the hereditary form of Alzheimer’s disease that strikes early in life.
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Biomarkers show promise as Alzheimer’s diagnostic tool
Physical biomarkers have been discovered that may help diagnose the changes to proteins found in the spinal fluid and blood of Alzheimer's patients...
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Study identifies new brain death pathway in Alzheimer’s disease
Evidence that the activation of a biological pathway necroptosis is closely linked with Alzheimer's...
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Two new genes linked to Alzheimer’s risk
Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.
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Scientists uncover the structure of tau filaments from Alzheimer’s disease
Researchers at the MRC Laboratory of Molecular Biology (LMB) have, for the first time, revealed the atomic structures of one of the two types of the abnormal filaments which lead to Alzheimer's disease.
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Western diet increases Alzheimer’s pathology in predisposed mice
Obese mice with a particular version of a gene strongly associated with Alzheimer's disease (AD) in humans show increased Alzheimer's pathology, according to new research published in eNeuro.
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Insights from discovery through clinical efficacy to support a new class of therapeutics in Alzheimer’s disease
Research into innovative small molecule therapeutics with disease modifying potential in Alzheimer’s disease (AD) has been conducted at Alzheon since 2013.
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Alzheimer’s, Parkinson’s, and Huntington’s diseases share common crucial feature
A study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a ability to cause damage...
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Spread of tau protein measured in the brains of Alzheimer’s patients
In a new study researchers measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer’s disease.
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New cell separator could advance cancer and Alzheimer’s research
A new cell separator that began life as a tinfoil and epoxy glue prototype built with supplies from a University shop could revolutionise stem-cell and regenerative cell-based therapies.
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Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
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Cell death research shows promise for preventing Alzheimer’s
Alzheimer’s disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. Currently, the predominant theory behind Alzheimer’s disease is the “amyloid hypothesis,” which states that abnormally increased levels of amyloid beta (Aβ) peptides outside of brain cells produce a variety of low molecular weight…
