Drugs with potential to stop plaque build-up in arteries identified
A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
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A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
Glycosaminoglycans (GAGs) are a class of naturally occurring polysaccharides that play vital roles in cellular functions. GAGs (eg, hyaluronic acid, heparosan, chondroitin, chondroitin sulfate, heparan sulfate and heparin) have also been utilised in biopharmaceutical and nutraceutical industries. Animal-sourced GAGs can contain process impurities and contaminants, which may result in adverse…
The study shows how drug-like small molecules inhibit the activity of Transient Receptor Potential Canonical 1/4/5 (TRPC1/4/5) channels and could transform the development of future therapies.
Scientists suggest the PCSK9Q152H gene variant may act as a “fountain of youth”, allowing people to live longer, healthier lives.
Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
Pharmaceutical company, Sanofi, will eliminate jobs in France and Germany and end new in-house cardiology research programmes.
The new class of drugs are mechanism-based inhibitors which potentially interrupt the gut microbial pathway that produces TMAO...
A new study has identified a pattern of inflammation associated with cardio-metabolic risks...
A new study has found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues...
Study suggests that chronic inflammation in the elderly -- thought to be involved in many age-related diseases -- is due to imbalances in gut bacteria...
New studies add to evidence of link between mitochondrial DNA copy number and risk for cardiovascular disease...
The University of Zurich is launching a new WHO Collaborating Centre for Physical Activity and Health. The Physical Activity and Health Unit and other groups of the Epidemiology, Biostatistics and Prevention Institute will support the Physical Activity Strategy for the World Health Organization (WHO) European Region.
A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.
29 September 2016 | By Niamh Louise Marriott, Digital Content Producer
It is difficult to estimate the global burden of cardiovascular disease in people with diabetes, due to lack of data and standardisation...