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Chemical probe switches off two cancer-causing proteins
26 October 2015 | By Victoria White
The discovery sheds new light on the role these proteins play in driving cancer cell proliferation...
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Study shows immunosuppressive effects of CA125 on farletuzumab
26 October 2015 | By Victoria White
The new findings have led to the hypothesis that patients with high levels of CA125 have an immunosuppressive tumour microenvironment that may potentially enable cancer cells to escape immune-mediated cytotoxicity...
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Disease recreated in mini-kidney organoids in the lab
23 October 2015 | By Victoria White
The work paves the way for personalised drug discovery for kidney disease...
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Gene discovery could lead to new treatments for sepsis
22 October 2015 | By Victoria White
Scientists have isolated the gene that produces Gasdermin-D - a protein that plays a critical role in the pathway to sepsis...
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Launch of Dementia Discovery Fund to deliver new dementia treatments by 2025
21 October 2015 | By Kate Douetil
This innovative new global investment fund has gained support from a wide variety of investors, including the UK Government’s Department of Health (DoH), Alzheimer’s Research UK and world-leading major pharmaceutical companies Biogen, GlaxoSmithKline, Johnson & Johnson, Lilly, Pfizer and Takeda...
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Domainex and ICL team up to discover myocardial infarction therapies
20 October 2015 | By Victoria White
Domainex has been selected as Imperial’s strategic drug discovery partner to provide services including biochemical and biophysical assay development...
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Positive results for DelMar’s VAL-083 in ovarian cancer
19 October 2015 | By Victoria White
Preclinical data demonstrate the effectiveness of VAL-083 against cisplatin-resistant ovarian cancers...
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Nuevolution in drug discovery collaboration with Janssen
19 October 2015 | By Victoria White
Within the framework of the collaboration, Nuevolution will apply its drug discovery platform Chemetics to discover and advance drug candidates...
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York scientists one step closer to finding a new generation of antibiotics
16 October 2015 | By Victoria White
The scientists used novel genetic engineering tools to manipulate the genes required for antibiotic biosynthesis...
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Researchers describe new molecular markers for high-risk neuroblastoma
16 October 2015 | By Victoria White
Researchers have identified previously unknown genomic alterations leading to up-regulation of the telomerase reverse transcriptase gene (TERT). Overexpression of TERT is often associated with cancers and tumour formation...
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OICR, Novera and Janssen to develop haematological cancer therapies
15 October 2015 | By Victoria White
As part of the collaboration, Novera will discover and develop novel therapeutic compounds identified through OICR's drug discovery programme...
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GPR3 identified as a new target for Alzheimer’s disease treatment
15 October 2015 | By Victoria White
Researchers have determined that the protein GPR3 might play an important role in alleviating the cognitive deficits of 'amyloid plaques'...
whitepaper
App Note: Easy Particle Analysis for Viscous Samples with MFI
In this application note, learn how the manual MFI 5000 performs accurate particle analysis for viscous protein therapeutics, offering size, count and morphology...
whitepaper
App Note: Achieving 21 CFR Part 11 Compliance with the iCE3
Rapid analysis, platform methods and easy method development make the iCE3 ideal for analyzing biologics...
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Researchers develop animal-free renal screening platform
13 October 2015 | By Victoria White
Researchers have developed the first animal-free screening platforms capable of predicting the toxic effects of compounds on the human kidney accurately...
