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Alzheimer’s, Parkinson’s, and Huntington’s diseases share common crucial feature
A study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a ability to cause damage...
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Stem Cells
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Cancer drug proves effective against common allergies
A cancer drug for patients with certain types of leukaemia and lymphoma can also prevent reactions to some of the most common airborne allergens, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.
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Protective responses appear weaker in neural stem cells from HD patients
A multi-institutional team based at Massachusetts General Hospital (MGH) has discovered how a potential treatment strategy for Huntington disease (HD) produces its effects, verified its action in human cells and identified a previously unknown deficit in neural stem cells from patients with HD.
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Antibodies as ‘messengers’ in the nervous system
Antibodies are able to activate human nerve cells within milliseconds and hence modify their function.
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Researchers discover neural stem cells that can become blood vessels
This finding could have a great impact on the study of paediatric tumours, as it could already constitute one of the factors that produces their growth.
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Scientists to test Zika virus on brain tumours
The research, using tumour cells in the laboratory and in mice, will see if the Zika virus can destroy cancer cells.
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New gene variant identified in ALS provides treatment hope
A new study shows that a variant in UBQLN4 gene has been associated with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS). The study also describes how this gene variant disrupts a cellular process that drives motor neuron development. This new insight opens the door to potential treatment targets for…
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New counterintuitive approach to treating brain cancer
The loss of the tumour suppressor gene PTEN has been linked to tumour growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM).
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Researchers find key molecule that could lead to new anaemia therapies
Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.
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Using single-cell RNA sequencing to track stem cell development
Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.
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New lung ‘organoids’ in a dish mimic features of full-size lung
'Mini organs' may aid in understanding and treating respiratory diseases.
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Lung study in mice points to new therapies to treat critical illness
Scientists have pinpointed a chemical signal that worsens inflammation linked to a life-threatening lung condition. The discovery could eventually lead to new therapies for this disease, which can be fatal for up to half of those affected.
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Immune cells found to be derived from specialised progenitors
Dendritic cells are gatekeepers of immunity and crucial for the detection and initiation of immunity against pathogens and foreign substances. Up to now, dendritic cell subtypes were thought to develop from one common progenitor. New findings from a team of researchers show with single cell resolution that this important component…
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New genes identified in children linked to stress & bipolar disorder
Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a new study...
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A new bioinformatics tool to decipher evolutionary biology
Understanding evolution is one of the cornerstones of biology - evolution is, in fact, the sole explanation for life's diversity on our planet. Based on the evolution of proteins, researchers may explain the emergence of new species and functions through genetic changes or how enzymes with novel functions might be…
