A2aAR protein holds clues for better drug design
Scientists have investigated a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases...
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Researchers create anti-inflammatory antibodies to treat autoimmune disease
Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
FDA approves gene therapy for rare form of vision loss
FDA approves Luxturna for patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy.
CRISPR prevents hearing loss in mice
Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.
Faulty gene could be responsible for some Crohn’s disease cases
Interaction between MDR1 gene and TH17 immune cells in the ileum could hold the key to Crohn's disease in some instances.
MG1 virus destroys HIV-infected cells that standard therapies can’t reach
Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.
Assay may boost targeted treatment of non-hodgkin lymphoma
Better subtyping of diffuse large B-cell lymphomas can enhance diagnosis and guide treatment...
Chemical oscillators offer a new level of molecular control
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit computation within molecular systems...
Joint policy document shows the potential impact of Brexit
The associations representing the European and British life science industry have launched a joint policy document on the potential impact of the United Kingdom’s exit from the European Union...
Mechanism identified of impaired dendritic cell function that weakens response to cancer
New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...
F50/T50 combination provides artificial ovary prototype
A protein formulation based on fibrin resembles the architecture and rigidity of human ovarian tissue and could be used for ovary transplant...
Groundbreaking gene therapy trial set to cure haemophilia
A cure for haemophilia is one step closer, following results of a gene therapy trial led by the NHS in London.
How good design improves energy efficiency
In April 2018, changes to energy efficiency regulations will mean that every non-domestic privately rented property must have an EPC rating of at least an E. Here, John Rush, discusses three tips for improving the energy efficiency of HVAC systems in laboratories...
Using 3D cell cultures to fight anti-cancer therapy resistance
An international team of researchers have developed 3D cell cultures in which genes can be specifically modified to improve the use of targeted anti-cancer drugs...
Quorum-sensing inhibitors may improve treatments for cystic fibrosis patients
Researchers have identified a promising solution to improving treatments offered to patients with cystic fibrosis that could lead to the development of new personalised therapies...
