A new strategy to overcome tumour-induced immunosuppression
Researchers have found that blocking key enzymes could boost anti-cancer T cell responses and resistance to immunosuppression.
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New findings could lead to a vaccine that can offer protection against emerging COVID-19 variants
Scientists have discovered antibodies that are effective against many different COVID-19 variants.
Universal flu vaccine protects against influenza A and B viruses
Vaccinating mice with this universal flu candidate induced broad neuraminidase inhibition, M2 ectodomain specific antibodies and T cell immune responses.
How to tackle the immense challenge of delivering vaccines
Researchers have developed a safe and versatile platform to increase the thermal stability of vaccines and improve their transportability.
New generation of COVID-19 vaccines show promising results
Researchers have designed a COVID-19 vaccine to be less sensitive to mutations and equipped for future strains.
How T cells migrate from the tissue to the lymph nodes
Scientists have found that unconventional T cells migrate from tissue into the lymph nodes and influence immune responses there.
Optimising human small intestinal organoids by implementing Paneth cells
Researchers have succeeded in developing organoids that contain mature Paneth cells, which were not present in the previous human small intestinal organoids.
Scientists develop promising new gonorrhoea antibiotic
The drug candidate, JSF-2659, has been developed to be administered orally, and could be a game changer in treating gonorrhoea.
Stem cells could repair spinal cord injuries
Researchers have identified latent stem cells that could respond to spinal cord injuries.
Study reveals novel insights into Crohn’s disease
The findings by Massachusetts General Hospital could point to a potential target to treat Crohn’s disease.
A modified TB vaccine could treat bladder cancer
An animal study has shown that a modified vaccine for tuberculosis could treat bladder cancer whilst minimising side effects.
Genomic studies could impact pneumococcal disease vaccine design
A recent genomic surveillance study has demonstrated the value of genomics to inform vaccine design and highlight the challenge posted by shapeshifting bacteria.
Researchers develop a small molecule that makes immunotherapy available to all cancer patients
Scientists have identified and synthesised a small molecule that could be a more accessible and affective alternative to an antibody that treats a wide range of cancers.
New vaccine protects mice against RSV
The new RSV vaccine formulation protected newborn mice against infection and evoked strong responses in immune cells from human newborns.
First captured image of antigen-bound T-cell receptor at near-atomic resolution
Using cryo-electron microscopy, researchers have captured the structure of a membrane-bound T-cell receptor complex with bound antigen.
