Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
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Harvard Medical School
A study has used artificial intelligence to reveal adeno-associated virus (AAV) capsid variants for use in gene therapies.
New research has provided a metabolic atlas for insights into obesity and tumours' ability to hide from the immune system.
The field of oncology has successfully applied precision medicine approaches to diagnosis and treatment. Success has been driven by a growing understanding of the underlying biology of cancer; the emergence of innovative tools and technologies for biomarker identification and detection; and considerable advocacy by patients, physicians and policymakers that has…
Five immune response biomarkers have been identified by researchers who say they can be used to classify which COVID-19 patients will survive the disease.
Researchers have found the small molecules Apilimod and Vacuolin-1 inhibited the PIKfyve kinase in cells, preventing infection from Zaire ebolavirus and SARS-CoV-2.
The novel aryl hydrocarbon receptor (AHR) inhibiting drug slowed zika virus replication and prevented mouse foetuses malforming in infected mothers.
Scientists have created the first lab-dish models of the cellular clock, where each 'tick' stimulates the formation of the vertebra, which uses stem cells derived from adult human tissue.
Research has found that bile acids, converted by gut microbes, act as inflammatory regulators in IBD by modulating the differentiation of T cells in the gut.
'Prime editing', a new CRISPR genome-editing approach, is capable of directly editing human cells in an accurate and efficient way.
This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.
New research into sex-based differences of Parkinson's disease could lead to new treatments.
A recent study has uncovered a key mechanism that allows some of the world's deadliest viruses to replicate.
This research advances the possibility of reviving the heart's regenerative capacities using microRNAs.