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Chemotherapy success calculated by new machine learning model
Percent necrosis calculated with machine learning model for patients with osteosarcoma provides an accurate prognosis for survival.
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Johns Hopkins Medicine
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Researchers generate organoid model for gastroesophageal junction cancer
The scientists discovered that dual knockout of genes in organoids grown from human tissue can generate a model of a potential therapeutic target for gastroesophageal junction cancer.
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New treatment target discovered for sleep apnoea
A recent study in mice revealed that an ion channel already proven to affect blood pressure in obese mice plays a role in suppressing their breathing, influencing sleep apnoea.
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Scientists have identified novel molecular biomarkers in cells that spread triple-negative breast cancer
The researchers identified key molecular differences between triple-negative breast cancer cells that cling to an initial tumour and those that venture off to form distant tumours.
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Scientists create a nanobody that could treat Parkinson’s disease
Researchers have developed a nanobody that can penetrate the tough exterior of brain cells and untangle misshapen proteins that lead to Parkinson’s disease.
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Clearer imaging approach captures images of blood vessels
Researchers have developed a new imaging approach that can capture blood vessel images at different spatial scales.
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Epigenome editing used to reverse gene mutation in mice
A study has demonstrated the success of changing the genome of mice, regulating the production of the C11orf46 gene.
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Transplanted brain stem cells survive without anti-rejection drugs in mice
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
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pH imbalance in astrocytes may lead to Alzheimer’s disease
The researchers found that 10 of the 100 most frequently down-regulated genes were connected with proton flow in the cell...
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Thorase protein may be linked to schizophrenia
Epilepsy drug reverses anti-social behaviours in mice with genes that produce variant proteins...