news
Potential EBV-associated cancer treatment in small molecule inhibitors
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
List view / Grid view
The Wistar Institute
Filter the results
news
Protection against Mayaro virus using engineered DNA vaccine
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
news
DNA anticancer vaccine targets tumour neoantigens
A DNA vaccine developed through the use of unique tumour antigens could lead the way towards vaccinating people against cancer...
news
PCSK9 inhibitors to treat high cholesterol
Low-density lipoprotein cholesterol could be treated by using synthetic DNA-encoded monoclonal antibodies to inhibit PCSK9...
news
DNA vaccine shows promise for cancer immunotherapy
DNA vaccine optimised to cross-react with several MAGE-A isoforms generates a robust immune response and antitumour activity in a pre-clinical model of melanoma...
news
Pro72Arg gene variant increases tumour cell metabolism
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
news
Mechanism identified of impaired dendritic cell function that weakens response to cancer
New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...
news
DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
news
B-cells promote melanoma progression and resistance to therapy
Depletion of B cells in the tumour micro-environment shows anti-tumour activity in patients with advanced metastatic melanoma...
news
Novel immunotherapy technology for prostate cancer
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
news
New therapeutic approach for ovarian cancer identified
Scientists discover, a potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer...
news
NIH funds six research collaborations to find a cure for HIV
14 July 2016 | By Victoria White, Digital Content Producer
The US National Institutes of Health has awarded $30 million in annual funding to help advance science towards a cure for HIV...
news
Inovio and Wistar team up for DNA-based immunotherapies
16 March 2016 | By Victoria White
Inovio and the Wistar Institute are to research preventive and therapeutic DNA-based immunotherapies for cancers and infectious diseases...
news
PhoreMost and The Wistar team up to identify targets in cancer, immunotherapy and aging
10 March 2016 | By Victoria White
PhoreMost has entered into an alliance with The Wistar Institute to identify and de-orphan novel targets in cancer, aging and the immune system...