Pro72Arg gene variant increases tumour cell metabolism
1 March 2018 | By Dr Zara Kassam (Drug Target Review)
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
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Mechanism identified of impaired dendritic cell function that weakens response to cancer
15 December 2017 | By Dr Zara Kassam (Drug Target Review)
New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...
DNA-based Zika vaccine found effective at inducing immune response
5 October 2017 | By Dr Zara Kassam (Drug Target Review)
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
B-cells promote melanoma progression and resistance to therapy
21 September 2017 | By Dr Zara Kassam (Drug Target Review)
Depletion of B cells in the tumour micro-environment shows anti-tumour activity in patients with advanced metastatic melanoma...
Novel immunotherapy technology for prostate cancer
18 August 2017 | By Dr Zara Kassam (Drug Target Review)
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
New therapeutic approach for ovarian cancer identified
24 July 2017 | By Dr Zara Kassam (Drug Target Review)
Scientists discover, a potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer...
NIH funds six research collaborations to find a cure for HIV
14 July 2016 | By Victoria White, Digital Content Producer
The US National Institutes of Health has awarded $30 million in annual funding to help advance science towards a cure for HIV...
Inovio and Wistar team up for DNA-based immunotherapies
16 March 2016 | By Victoria White
Inovio and the Wistar Institute are to research preventive and therapeutic DNA-based immunotherapies for cancers and infectious diseases...
PhoreMost and The Wistar team up to identify targets in cancer, immunotherapy and aging
10 March 2016 | By Victoria White
PhoreMost has entered into an alliance with The Wistar Institute to identify and de-orphan novel targets in cancer, aging and the immune system...
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