Antibodies

Breast cancer progression may be halted with CRISPR gene editing

26 August 2019 | By Rachael Harper (Drug Target Review)

A tumour-targeted CRISPR gene editing system encapsulated in a nanogel could halt the growth of triple-negative breast cancer.

Flyer: Affinity Column for Fast Evaluation of ADCC Activity

22 August 2019 | By Tosoh

TSKgel FcR-IIIA-NPR is based on a recombinant FcγIIIa receptor ligand immobilized on a non-porous polymer particle. It allows fast assessment of biologic activity of monoclonal antibodies.

Tosoh Bioscience

Allergy-driving cells identified as potential drug targets

2 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.

OX40-expressing follicular helper T cells can control rheumatoid arthritis

1 August 2019 | By Rachael Harper (Drug Target Review)

New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.

Antibody therapy extends survival in mice with pancreatic cancer

1 August 2019 | By Rachael Harper (Drug Target Review)

Scientists have found a way to target and knock out a protein which is widely involved in pancreatic cancer cell growth, survival and invasion.

New therapy discovered to treat acute lymphoblastic leukaemia

30 July 2019 | By Drug Target Review

Researchers have discovered a new combination therapy to treat drug-resistant acute lymphoblastic leukaemia, tested in pre-clinical trials.

Enzo Life Sciences

Promising drug developed for ovarian and pancreatic cancers

22 July 2019 | By Drug Target Review

An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.

Whitepaper: IHC/ICC Protocol Guide

22 July 2019 | By Bio-Techne

Immunohistochemistry (IHC) and immunocytochemistry (ICC) are techniques employed to localize antigen expression and are dependent on specific epitope-antibody interactions.

Whitepaper: Neural Cell Culturing Guide

22 July 2019 | By Bio-Techne

The advent of in vitro culturing of neural cells has been central to driving our understanding of the nervous system.

Whitepaper: Immune Cell Isolation & Culture

22 July 2019 | By Bio-Techne

Immune cell isolation and culture are necessary for both basic research aimed at investigating the functions of different immune cell types, and for expanding specific immune cell populations for therapeutic purposes.

New potential liver cancer treatment found with biomarker-guided strategy

16 July 2019 | By European Pharmaceutical Review

A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.

Role of protein in spread of cytomegalovirus discovered

11 July 2019 | By Victoria Rees (Drug Target Review)

A study has revealed the role of a protein which enables human cytomegalovirus to spread, the number one cause of congenital birth defects in the world.

Discovering new routes to cancer drug discovery with neutrons

8 July 2019 | By Matthew Blakeley

From the world’s flagship neutron science facility, Institut Laue-Langevin (ILL), Matthew Blakeley shares insights into how they are harnessing the power of neutrons to aid their search for new cancer treatments.