news
NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
List view / Grid view
Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
news
Biomarkers identified that predict immunotherapy success
Researchers in Switzerland have identified biomarkers in the blood that can predict which patients are likely to respond favourably to immunotherapy treatment for cancer.
whitepaper
Application note: High throughput quantitation of cytokine biomarkers using LANCE Ultra TR-FRET assays
In this application note, PerkinElmer demonstrates the sensitivity, robust performance, and HTS suitability of the LANCE Ultra cytokine biomarker kits.
article
Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
article
Identification of hits and leads for human African trypanosomiasis
Neglected tropical diseases (NTD) affect more than one billion people and new targets and drugs are needed to tackle these infections. The multi-disciplinary NMTrypI consortium has identified a number of different compound classes which could be effective against these diseases. This article reviews some of these compounds...
news
Innovative probe visualises tumours
A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.
news
New weakness found in most common childhood malignant brain tumour
A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
news
Sperm RNA may serve as biomarkers of future health
Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study.
news
Asthma biomarkers identified from lung bacteria
New research suggests that the lung microbiome plays a significant role in asthma severity and response to treatment...
news
Mitochondrial DNA could predict risk for sudden cardiac death
New studies add to evidence of link between mitochondrial DNA copy number and risk for cardiovascular disease...
news
MAIT cells serve as biomarkers for diabetes
Scientists have discovered that the onset of type 1 diabetes is preceded by modification of MAIT lymphocytes...
news
CCL11 may allow early CTE diagnosis
Researchers have identified a new biomarker for chronic traumatic encephalopathy that may allow the disease to be diagnosed during life for the first time...
news
Metabolism can be used to subtype hepatoblastoma
Scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma...
news
Therapy proves effective in subgroup of COPD patients
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...
news
Biomarkers as effective at predicting sepsis as patient monitoring
Researchers have identified five key sepsis biomarkers and looked at whether they had the same or better predictive power as traditional methods...
