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Article: Defeating COVID-19: The science behind a new ELISA
Discover how a new ELISA against S1-RBD for COVID-19 seroconversion detection can accelerate discovery to facilitate vaccine breakthroughs.
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Cell Cultures
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Application note: Effectiveness of CRISPR‑Cas9 using pools of synthetic crRNAs in high-content analysis screening experiments
In this application note, discover how pools of synthetic crRNAs can produce a phenotype as strong as, or stronger, than any one of the component crRNAs in arrayed CRISPR screening experiments.
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Which CHO cell is the right CHO cell?
Dr Louis Boon offers guidance on how to select the best CHO cell for the upstream bioprocessing of biologics. He also explains how automation can aid monoclonality and why the most efficient approach during the development of biological drugs is to utilise an established cell line platform.
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Scientists develop synthetic cell that grows and divides uniformly
Researchers have created a single-celled synthetic organism able to grow and divide that could be used to produce drugs and detect disease.
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Hydrogel used to revert cancer cells back to cancer stem cells
A new hydrogel has been shown to convert cancer cells to cancer stem cells within 24 hours, in six different human cancer cell line types.
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Drug Target Review – Issue 1 2021
In this issue, find articles discussing how high-throughput experimentation can enhance automated molecular discovery, why bNAbs present a promising COVID-19 treatment and how a novel rhinovirus vaccine was developed. Also included are features on immuno-oncology, cell line development and assays.
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Catalogue: Cell isolation with Dynabeads
Magnetic separation with Dynabeads helps ensure that the isolated cells are not affected by passage through a dense column.
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Catalogue: Nuclease-Free tubes, tips & buffers
Working with RNA requires rigorous nuclease contamination controls in place. Stock up on Nuclease-Free tubes tips and buffers #Back2Lab
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Team uses antibodies to tag disease-related proteins for destruction
Researchers have developed a technique utilising antibodies to tag disease-causing proteins, to treat the underlying causes of disease.
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Researchers develop model of early human embryo from skin cells
Scientists have created the first model of early human embryos by reprogramming fibroblasts into a blastocyst-like structures.
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RNA reference guide: Learn the basics of RNA isolation
The extraction and isolation of RNA is essential in many downstream applications. Check out the basics of RNA isolation from Thermo Fisher.
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Podcast: SARS-CoV-2 molecular testing
New podcast on SARS-CoV-2 molecular testing: From human sample analysis to Wastewater Surveillance.
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Catalogue: Ribosomal RNA from bacteria with RiboMinus
RiboMinus Bacteria 2.0 Transcriptome Isolation Kits perform efficient transcriptome enrichment from total bacterial RNA. Improve your RNA extraction from bacteria today.
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New inhibitor found to combat drug-resistant cancer cells
A team has developed a novel inhibitor that blocks a protein in cancer cells, making drug-resistant tumours respond to chemotherapy.
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SARS-CoV-2 mAb cocktail effective against all known variants of virus
A monoclonal antibody (mAb) cocktail, that targets sites on the Spike protein other than the E484K residue, can neutralise SARS-CoV-2.
