whitepaper

Case study: Parkinson’s disease modelling for drug discovery

Posted: 11 May 2021 | | No comments yet

The development of a Parkinson’s disease model, using hiPSC-derived neural cells, to assess alpha-synuclein pre-formed fibril-induced toxicity.

Misfolding and aggregation of alpha-synuclein proteins is believed to drive neurodegeneration, and plays a key role in the pathogenesis of Parkinson’s disease. Ncardia created a disease model from a co-culture of hiPSC-derived neurons and astrocytes, that recapitulate these typical pathological features, to enable investigation of the disease pathogenesis and to provide specific and valuable readouts for drug discovery for Parkinson’s disease.

    To read this case study in full, please complete the form below:

     









    This specialist content is provided to you free-of-charge thanks to the kind support of Ncardia

    By clicking submit you confirm that you accept our terms and conditions and privacy policy.

    Leave a Reply

    Your email address will not be published. Required fields are marked *