Disease Research

Scientists discover over 7,000 effective antibiotic combinations

3 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...

The changing face in drug discovery

1 September 2018 | By Pushpanathan Muthuirulan

Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…

Parkinson’s disease: An endogenous protein might become a candidate for drug development

31 August 2018 | By Drug Target Review

Researchers have deployed a bacterial import signal in order to deliver Nurr1 into cells...

Venoms could be used to treat cancer and autoimmune diseases

31 August 2018 | By Iqra Farooq (Drug Target Review)

Venoms are continually being researched as potential chemicals for medicinal therapeutics to treat autoimmune diseases and diabetes...

Matcha green tea kills cancer stem cells

31 August 2018 | By Iqra Farooq (Drug Target Review)

Researchers have found that Matcha green tea has properties to combat breast cancer stem cells...

Inhibiting NF-κB improves heart function in Duchenne muscular dystrophy

31 August 2018 | By Drug Target Review

Breakthrough research has uncovered an unexpected mechanism that underlies cardiomyopathy in DMD...

Dectin-1 pathway may be crucial for treating fungal inflammation and pain

30 August 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified the dectin-1 pathway as being a potential target for the treatment of pain associated with candidiasis...

Potential drug to cure ciliopathies

30 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a potential treatment that will be a foundation for developing drugs for various genetic disorders...

NF-2 gene mutations make cells hyper-responsive to growth factor signalling

29 August 2018 | By Drug Target Review

Researchers have determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation...

Beckman Coulter, Inc.

Brain-heart link points at potential biomarker for trauma-induced epilepsy

28 August 2018 | By Drug Target Review

Scientists at Penn State find that heartbeat irregularities connected to brain activity abnormalities may pave the way to predict onset of epilepsy in certain patients…

The molecular link between ageing and neurodegeneration

28 August 2018 | By Drug Target Review

Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...

NanoMIPs efficiently target and eliminate cancer cells

24 August 2018 | By Dr Zara Kassam (Drug Target Review)

A joint research team has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs...

Powerful molecules provide new findings about Huntington’s disease

23 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...

Experimental drug targets cancers associated with Epstein-Barr virus

23 August 2018 | By Iqra Farooq (Drug Target Review)

An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...