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Novel technique reveals Parkinson’s changes how neurons sense oxygen
The new approach enables researchers to isolate brain cells associated with Parkinson's disease and study their gene expression patterns.
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LMTK3 inhibitors could be an effective breast cancer therapy, say scientists
Researchers demonstrate that inhibiting the LMTK3 kinase is an effective anticancer strategy in murine models of breast cancer.
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Primate model used to explore features of SARS-CoV-2 infection
The non-human primate model exhibited a COVID-19-like disease and showed how symptoms and viral activity change over the course of SARS-CoV-2 infection.
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Researchers suggest SKI complex of SARS-CoV-2 as novel drug target
Researchers have discovered new drug compounds that target the SKI complex of SARS-CoV-2, preventing replication.
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Researchers dicover novel targets for rheumatoid arthritis therapies
Researchers have identified that autoreactive B cells and a protein that enables them to invade joints could be promising drug targets for the most common inflammatory arthritis.
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Researchers reveal structure of SARS-CoV-2 Envelope protein
The molecular structure of the SARS-CoV-2 Envelope protein has been identified by researchers using nuclear magnetic resonance.
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Furin cleavage motif makes SARS-CoV-2 more aggressive than other CoVs, find scientists
A specific furin cleavage motif on the SARS-CoV-2 Spike protein, not present on other coronaviruses (CoVs), could be targeted by novel COVID-19 therapies.
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Cell line development services market to grow at 13.3 percent
Reports suggest the market growth is driven by advances in biotechnology and its applications, as well as COVID-19 research.
![robotic hand pipetting from petri dish of organoids next to a clock - idea of automation speeding up organoid development [Credit: Daria Sokol/MIPT Press Office].](https://www.drugtargetreview.com/wp-content/uploads/algorithm-accelerating-organoid-development.jpg)
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Researchers accelerate organoid development and selection using algorithm
The semi-automated process enabled researchers to make retinal organoid production and selection nearly four times faster.
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RNA structures of SARS-CoV-2 reveal potential drug targets
The SARS-CoV-2 RNA genome structure has been studied by researchers who identified several potential drug targets.
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T cells facilitate chronic lung injury in the elderly after viral infections, finds study
After viral pneumonia in elderly mice, there is an accumulation of dysfunctional tissue-resident memory T cells in the lungs which scientists suggest may drive chronic inflammation and fibrosis.
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Pre-existing coronavirus antibodies could protect against new COVID-19 strains
Researchers have found antibodies, from infection with common cold coronaviruses, can also target SARS-CoV-2 - especially in children.
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Researchers discover how SARS-CoV-2 infects and replicates in host cells
A team has revealed how SARS-CoV-2 infects cells, suggesting that targeting its RNA with drugs would stop the virus replicating.
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Children produce a different antibody response to SARS-CoV-2 infection, finds study
A new analysis reveals that the course of SARS-CoV-2 infection and the immune response it provokes is completely different in adults and children.
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D614G mutation may make SARS-CoV-2 more contagious
According to a new study, the SARS-CoV-2 virus is accumulating genetic mutations, including one called D614G which may have made it more contagious.
