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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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Disease Research
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Scientists decipher 3D structure of promising molecular target for cancer treatment
Columbia University discovery could be a major step in developing therapies for cancer, controlling cholesterol...
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Gut microbiome directs immune system to fight cancer
The advent of immune checkpoint inhibitors is a major breakthrough in cancer immunotherapy...
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Paving the path towards precision medicine
A method to view the immune cell 'landscape' of bowel cancer tumours could pave the way towards more individualised medicine and treatment...
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Epigenetic protein could be new therapeutic target in acute myeloid leukemia
The epigenetic protein, EZH2, was found to delay the development of acute myeloid leukemia (AML) but also switches sides to maintain tumour growth...
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Ticagrelor reversal agent provides immediate and sustained relief
A reversal agent that sustains immediate relief from the side effects of ticagrelor stopping major bleeding, such as gastrointestinal hemorrhage...
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Optical imaging technique to detect tiny tumours
A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
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Potential EBV-associated cancer treatment in small molecule inhibitors
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
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Salamander gene partnerships could help spinal cord regeneration
Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
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Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori
Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
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Genomics to match treatments to pancreatic cancer patients
Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
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Protein marker in response to brain cancer therapy
An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
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Genetic study confirms that numerous genes contribute to Tourette’s syndrome
A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
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Colon cancer pathway discovery could lead to targeted therapies
Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer...
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Counteracting T-cell exhaustion in CAR-T cancer therapies
Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
