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Automated plasmid purification workflow developed for mammalian cell expression-quality DNA
Eli Lilly scientists report that they have designed, qualified and enabled a high-throughput plasmid purification and quantification workstation.
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Previous studies of human microbiome may be biased in favour of Global North
A new study has suggested that previous global research into the human microbiome is heavily biased in favour of wealthy countries such as the US and UK.
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New model yields promising gene therapy for heart condition
Scientists in Japan have developed a credible heart cell model for arrhythmogenic cardiomyopathy and observed a positive response in the condition using PKP2 gene therapy.
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Genes newly linked to ageing and human lifespan
Researchers have found that genes in small organisms, known to extend lifespan, could also impact ageing in humans.
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Scientists develop means to boost the power of CRISPR
The capability to edit genes has been transformative in opening therapeutic avenues for hitherto untreatable diseases and aiding biological insight. Scientists have now discovered a way to enhance this process using retrons, making the process more efficient and effective.
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Product hub: Introducing the latest addition to Thermo Fisher Scientific’s genome editing portfolio – InvitrogenTM TrueCutTM HiFi Cas9 Protein!
Read about the latest addition Invitrogen™ TrueCut™ HiFi Cas9 Protein to support your application and research goals.
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Three RNA-expression states may reveal cancer drug susceptibility
Scientists identified three prototypical RNA-expression states and revealed differences in their susceptibility to a variety of cancer drugs.
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Improving the safety of CRISPR for the clinic
Dr Danilo Maddalo from Genentech outlines the main benefits of CRISPR within the clinical realm and highlights some of the safety concerns that must be considered before CRISPR products reach patients.
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Experimental enzyme treatment protects mice from lethal anthrax infection
All mice infected with anthrax spores were completely protected after treatment with a pegylated enzyme known as PEG-CapD-CPS334C.
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Groundbreaking gene-editing method creates single-sex mice litters
The exciting new study demonstrates how the technology could be used to improve animal welfare in scientific research and agriculture.
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ACE2 receptor opens up precision approach against COVID-19
Researchers discover a new precision strategy to hinder the infection of the coronavirus, leading to the filing of a new drug patent.
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New approach improves avoidance of ‘bystander’ edits in CRISPR-base editor treatments
Rice University scientists have refined specific CRISPR-base editing strategies to avoid errors that occur during gene editing.
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Researchers achieve DNA methylation removal in mouse models
The study used CRISPR to show that DNA “de-methylation” activity can be targeted to anywhere in the DNA and may be a new therapeutic strategy.
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New single-cell and metagenomic technique can characterise microbes
The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.
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Mission Therapeutics receives $500k grant for Parkinson’s research
Mission Therapeutics was granted $500,000 from the The Michael J Fox Foundation for Parkinson’s Research for DUB inhibitor testing.
