news
Charles River Laboratories makes investments in high-throughput screening infrastructure
Signs collaboration agreement with AstraZeneca to offer state-of-the-art technology to clients.
List view / Grid view
Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
news
New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
webinar
Streamlining drug discovery assays for cancer and cardiovascular disease
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.
news
Novel curative gene therapy treatment for pulmonary fibrosis in mice
Researchers in Spain have developed a method of gene therapy that cures pulmonary fibrosis in mice by lengthening telomeres – the protective protein sections at the end of chromosomes.
whitepaper
Application note: Distinguishing cell types by phenotypic profiling
Describing how a single nuclear stain can enable phenotypic profiling for new and additional perspectives on assays at no extra cost.
news
Corning to introduce new dissolvable microcarriers for improved large-scale cell expansion
Corning to unveil new product offerings at Cell & Gene Therapy World in Miami, Fla.
news
Research enables screening millions of human antibodies for new drug discovery
Researchers have outlined a pioneering method of screening a person’s diverse set of antibodies for rapid therapeutic discovery.
news
Drugs targeting the cells circadian rhythm offers hope for glioblastoma
An experimental drug demonstrated selective cancer-killing ability against breast, colon, leukaemia, brain and melanoma cancer cells with no apparent effects on normal cells...
news
Promising preclinical drug candidate suppresses HIV
A team of researchers have tested a chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose...
news
Anti-obesity drug shrinks fat without suppressing appetite
Researchers have discovered a drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism...
article
Rational drug design: How far have we come?
From the early use of Hansch parameters and Topliss Trees to today’s computational structure–activity techniques, medicinal chemists have long sought to rationalise drug design to find the quickest and most resource-efficient route to market. But while modern strategies are more reliant on statistical algorithms and vast data libraries, these founding…
news
Thorase protein may be linked to schizophrenia
Epilepsy drug reverses anti-social behaviours in mice with genes that produce variant proteins...
product
Alpha technology
3 January 2018 | By PerkinElmer
Alpha (Amplified Luminescence Proximity Homogeneous Assay) bead-based technology for no-wash assays.
news
A2aAR protein holds clues for better drug design
Scientists have investigated a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases...
news
MG1 virus destroys HIV-infected cells that standard therapies can’t reach
Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.
