news
Single enzyme provides target for new sepsis drugs
Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
List view / Grid view
Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
news
Study identifies virulence factors of Leishmania
Researchers have discovered the mechanism behind the spread of Leishmania, indicating a potential drug target.
news
Molecule identified as key in pancreatic cancer metastasis
New findings show that the environment for pancreatic cancers plays a role in its metastasis, revealing a new potential drug target.
news
Four cell types discovered in glioblastoma tumours
A new study has revealed that glioblastomas contain four different types of cell which the researchers say should be treated separately.
article
Five newest developments for imaging in drug research
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
news
Experimental compound could be used to treat pancreatic cancer
Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.
news
Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
news
Allergy-driving cells identified as potential drug targets
Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.
news
Study reveals cancer cell fuelling mechanism
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
news
OX40-expressing follicular helper T cells can control rheumatoid arthritis
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
news
Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
news
Researchers discover new neuroblastoma drug target
A study has discovered that reducing expression of a key gene in neuroblastoma tumourigenesis is an important drug target for the condition.
news
Study identifies potential drug target for prostate cancer
Researchers have discovered a non-coding RNA which could be used as a biomarker and in new therapies for prostate cancer.
news
No-cut CRISPR could be used to treat muscular dystrophy
Researchers have successfully used a no-cut CRISPR gene editing technique as a therapy for muscular dystrophy in mice models.
article
Encouraging drug discovery and therapeutic targets for dementia
A review has been published by experts in neurodegeneration research, detailing six ways to improve dementia research. This article investigates one of these suggestions, focusing on how we can improve drug target identification.
