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New study could lead to better treatments for autoimmune diseases
A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.
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Immunology
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New insights found into lupus may help combat the disease
A new study may lead to new treatments for lupus as it has found that, when impaired, a key regulator of the immune system can cause damaging immune system attacks on skin and organs, which are hallmarks of the disease.
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Cancer immunotherapies may be improved with early immune response
A new mechanism has been reported for detecting foreign material during early immune responses which may help detect elusive cancers.
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Scientists discover how strep bacterium hides from the immune system
Produced by Group A Streptococcus, researchers have discovered the S protein, which binds to the red blood cell membrane to avoid being destroyed by immune cells and could be a target for anti-virulence drugs.
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Protein tag developed to aid in study of the immune system
A novel approach to better understand a basic defence mechanism of the immune system has been developed using the ISG15 protein which could lead to novel antimicrobial drugs.
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Restarting metabolic process could make sarcoma susceptible to treatment
Researchers have found that soft tissue sarcoma cells stop a key metabolic process which allows them to spread and restarting that process could leave these cancers vulnerable treatments.
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Dengue vaccines may be improved by simulating amino acid starvation
Scientists have discovered that a plant-based compound called halofuginone activates a pathway that results in better antibodies and could improve the effectiveness of vaccines.
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MAIT immune cells revealed as key in toxic shock development
Researchers have found that MAIT immune cells respond rapidly to group A streptococcal infection, causing inflammation and toxic shock, which presents a therapeutic target.
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Lung response to bacteria revealed by researchers
A study has discovered the process behind the lung immune response, which could be used to develop treatments against pneumonia.
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Better HIV, lupus and hep C treatments possible with malaria discovery
A new discovery on how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus.
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Potential new target found for inflammatory disease treatment
Molecules made by immune cells to transport sodium lactate could be a target for treatment to stop the lactate build-up in chronic inflammatory disorders.
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Study aims to boost antitumoral activity of compound in Amazon plant
Scientists seek to design therapeutically more potent chemicals from alkaloids produced by the plant, Uncaria guianensis, which could aid in combatting tumours.
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Immune response against skin-living virus could prevent skin cancer
It has been discovered that papillomaviruses induce immunity that protects patients, which could lead to a novel method for preventing skin cancer using a vaccine based on T cells.
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T cell homing beacons for lungs identified by researchers
Molecules that are critical for T cells to travel to and populate the lungs have been identified which could strengthen vaccines against influenza.
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Blocking specific macrophages leads to tumour shrinkage
A study has found that removing a particular kind of macrophage enables the immune system to attack tumours, providing a potential drug target.
