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Molecular Biology

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Exosome-based approach reduces levels of HIV in mice

23 September 2021 | By Anna Begley (Drug Target Review)

Scientists have used exosomes to deliver a novel protein that prevented HIV from replicating in the bone marrow, spleen and brain of mouse models.

article

Drug Target Review Vaccine Development ebook 2021

22 September 2021 | By Drug Target Review

Within this ebook, find articles examining the role of telomerase for universal cancer vaccines and discussing potential targets for neurodegenerative disease vaccines.

news

Scientists reveal that glioblastoma shows dependency on biotin distribution

15 September 2021 | By Anna Begley (Drug Target Review)

Researchers discovered that glioblastoma cells rely on biotin distribution for growth, leading to possible future drug combinations.

news

Gut microbiome linked to rheumatoid arthritis prognosis

15 September 2021 | By Anna Begley (Drug Target Review)

New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.

news

Gene therapy for Morquio A disease successful in rat model

14 September 2021 | By Anna Begley (Drug Target Review)

A novel gene therapy has fully corrected whole-body alterations in a rat model, paving the way for Morquio A therapies.

Microphage immune cell engulfing bacteria

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Immune cells found co-operating to capture and “eat” bacteria

13 September 2021 | By Anna Begley (Drug Target Review)

Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.

Pregnant woman having her blood pressure taken

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PP2A enzyme could be major driver of preeclampsia

10 September 2021 | By Anna Begley (Drug Target Review)

A new study found that protein phosphatase 2 (PP2A) found to be a major driver of preeclampsia, potentially leading to treatments.

news

Researchers simulate hepatitis B infection using computational method

8 September 2021 | By Anna Begley (Drug Target Review)

The new study modelled the process of capsid disassembly of the hepatitis B virus at an atomic level to help develop targeted therapies.

news

Genomic study uncovers causes of lung cancer in non-smokers

8 September 2021 | By Anna Begley (Drug Target Review)

An NIH study used whole genome sequencing to describe three molecular subtypes of lung cancer in non-smokers, possibly improving treatments.

news

Scientists discover mechanism behind cardiac hypertrophy

6 September 2021 | By Anna Begley (Drug Target Review)

New research has uncovered a mechanism underlying cardiac hypertrophy in mice, spurring novel avenues for potential treatments.

news

New screening method identifies COVID-19 protein inhibitor

3 September 2021 | By Anna Begley (Drug Target Review)

Researchers use fast and cost-effective technology to identify the viral protein inhibitor Mpro as a potential drug against COVID-19.

news

IAIPs shown to reduce ischemic stroke damage in pre-clinical study

2 September 2021 | By Anna Begley (Drug Target Review)

Inter-alpha inhibitor proteins (IAIP) demonstrated efficiency in reducing damage from an ischemic stroke, reveals pre-clinical study.

news

Study suggests how to develop intranasal vaccines for COVID-19 and flu

30 August 2021 | By Anna Begley (Drug Target Review)

New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.

news

Detergent-like APOL3 protein shown to kill bacteria in human cells

27 August 2021 | By Anna Begley (Drug Target Review)

Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.

news

Scientists develop novel strategy for tuberculosis vaccine

25 August 2021 | By Anna Begley (Drug Target Review)

A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.

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Molecular Biology