article
Drug Target Review Vaccine Development ebook 2021
Within this ebook, find articles examining the role of telomerase for universal cancer vaccines and discussing potential targets for neurodegenerative disease vaccines.
List view / Grid view
Molecular Targets
article
Drug Target Review – Issue 3 2021
In this issue, find articles exploring why CRISPR is useful for high-throughput drug discovery, how targeting telomerase may lead to universal cancer vaccines and a new study to identify therapeutics that can be repurposed against COVID-19. Also included are features on neuroscience, organoids and antibodies.
news
IL13Ra2 revealed as target against breast cancer-related brain metastasis
Interleukin 13 receptor alpha 2 was found in increased rates in cancer cells that metastasised to the brain and lungs, a new study has shown.
news
Club cell factors may reverse immune suppression in tumours
New research has revealed that club cells secret anti-immunosuppressive factors in tumours, potentially revolutionising cancer therapies.
article
Investigating neural oscillations in human brain organoids
This article delves into research at the University of California Los Angeles, US, where stem-cell derived brain organoids that can mimic electrical activity have been developed.
news
Eczema may stem from poorly regulated sex hormones, study finds
A breaking discovery has revealed the gene HSD3B1 that regulates the production of sex hormones is linked to atopic dermatitis (AD).
news
Controlling PTEN gene could combat paediatric rhabdomyosarcoma
The decreased expression of PTEN in mouse models was found to make rhabdomyosarcoma tumours more aggressive, highlighting new treatment approaches.
news
Scientists create organoid biobank to study SARS-CoV-2 genes
Researchers have established an organoid biobank to search for genes that are essential for the spreading of SARS-CoV-2 infection.
news
Researchers identify specific drug targets for a variety of brain disorders
Scientists have discovered drug targets in the neural circuits that encode memories, paving the way for the treatment of brain disorders.
whitepaper
Cell & Gene Therapy Advancements Whitepaper
Download this whitepaper to discover the latest research and developments in cell and gene therapies via exclusive articles and interviews.
news
Immune cells found co-operating to capture and “eat” bacteria
Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
news
Scientists create cellular blueprint of multiple sclerosis lesions
An NIH team have built a cellular map of chronic multiple sclerosis (MS) lesions to identify cells that drive inflammation and potential therapies.
news
PP2A enzyme could be major driver of preeclampsia
A new study found that protein phosphatase 2 (PP2A) found to be a major driver of preeclampsia, potentially leading to treatments.
news
STING-activating drugs could customise cancer treatments
An imaging technique identified emerging drugs that activate the STING protein to alter metabolic pathway activity in cancer cells.
news
Researchers simulate hepatitis B infection using computational method
The new study modelled the process of capsid disassembly of the hepatitis B virus at an atomic level to help develop targeted therapies.
