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Specific set of nerve cells controls seizures’ spread through brain
Experimental activation of a small set of nerve cells in the brain prevents convulsive seizures in a mouse model of temporal lobe epilepsy.
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Neurosciences
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Study indicates holistic nature of Alzheimer’s disease (AD) progression
A collaboration of scientists in the United States has identified a distinct association between inflammation biomarkers in blood plasma and cerebrospinal fluid (CSF), and markers of Alzheimer’s disease (AD).
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Systemic clearing of senescent astrocytes presents new therapeutic avenue for Parkinson’s disease
Researchers illuminate a new focal area for Parkinson’s disease therapy after demonstrating the beneficial effects of systemic clearing of senescent astrocytes.
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Raman imaging technique shows Alzheimer’s disease progress in the brain
Using Raman optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease...
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Energy storehouses in the brain may be source of Alzheimer’s
Research into the effects of Alzheimer’s disease on how mitochondria structures function has revealed that a highly toxic beta amyloid protein disrupts normal function.
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The combination of two proteins exerts a regenerating effect in Parkinson’s disease
Parkinson’s research has led to the development an experimental model that allows different stages of Parkinson’s disease to be reproduced.
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Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s
A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
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Human protein may aid neuron invasion by virus that causes hand, foot, and mouth disease
A human protein known as prohibitin may play a significant role in infection of the nervous system by EV71, one of several viruses that can cause hand, foot, and mouth disease.
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Patient-derived neural progenitor cells as a drug discovery model for mitochondrial diseases
Mitochondrial DNA (mtDNA) mutations cause severe disorders that are untreatable and mostly affect the nervous system. The difficulty in funding therapies may also be explained by the lack of viable modelling systems...
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Innovative probe visualises tumours
A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.
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New Alzheimer’s animal model more closely mimics human disease
Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.
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fMRI-neurofeedback shows promise in treating tinnitus
By using functional MRI researchers have found that neurofeedback training has the potential to reduce the severity of tinnitus or even eliminate it...
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Study reveals new mechanisms of cell death in neurodegenerative disorders
Researchers have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders...
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Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
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Metabolic collaboration linked to Alzheimer’s disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
