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New study discovers cancer-relevant protein shield
Researchers have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment...
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Proteomics
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
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IPSE protein has potential to alleviate debilitating disease
Chemotherapy-induced hemorrhagic cystitis alleviated by a protein that parasites use to keep hosts alive...
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Study changes long-held concepts of cell decoding
NIH scientists discover macromolecular complexes that could enable medication development...
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Scientists discover new causes of cellular decline in prematurely aging children
Researchers have uncovered new answers about why cells rapidly age in children with the rare and fatal disease, Hutchinson-Gilford Progeria Syndrome (HGPS).
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PARK14 protein associated with inflammation in Parkinson’s
Study overturns previous ideas about enzyme linked to many illnesses
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
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Modified PIP protein differentiates between cancerous and non-cancerous cells
A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
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EGFL7 protein provides a new treatment approach for MS
Researchers have discovered that the EGFL7 protein inhibits the migration of immune cells into the brain...
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Blockade of MT4-MMP protease increases blood-patrolling monocyte activity
Researchers in Spain have identified a function of the MT4-MMP protease (an enzyme that breaks down proteins) that could be targeted as a potential treatment for some infections, as well as tumour metastasis.
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Scientists create complex transmembrane proteins from scratch
Advance paves the way for the design of transmembrane proteins with useful new functions...
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Researchers evaluate tau phosphorylation related targets for Alzheimer’s research
Scientists in Moscow have extended the reach of QSP modelling by applying it to tau phosphorylation to better understand Alzheimer’s disease (AD) progression.
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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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Scientists halt breast cancer spread
Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.
