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Chemical tool developed to examine lipids in living cells
A new method has been developed by researchers using chemical tools activated by light to influence lipid concentration in living cells.
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Research & Development
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UK government funds 21 new research projects into COVID-19
A total of 21 COVID-19 research projects have been granted funding by the UK government, including vaccine and therapeutic development.
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Novel gene promoters could improve gene therapies for neurological diseases
Novel promoters based on those in the herpes viruses, enabled delivery of larger genes and increased the period they were active in the nervous system.
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Cynomolgus macaques: a promising animal model of COVID-19 infection?
Researchers comparing the effects of SARS-CoV-2, SARS-CoV and MERS-CoV in cynomolgus macaques suggest they could be an effective animal model for testing COVID-19 therapeutics.
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Universal Ebola vaccine shows promise in pre-clinical trials
An Ebola vaccine that has been tested in animals could potentially be used to neutralise four species of the virus, say the researchers.
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Drug compound used to overcome chemotherapy resistance in mice
Researchers testing 2-deoxy-D-glucose in mouse models of ovarian cancer report that the compound significantly improves the effectiveness of the chemotherapy drug, carboplatin.
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Specialised proteins could halt cytokine storms in COVID-19 patients
Researchers who developed modified proteins say this could be used in the fight against COVID-19, by tackling cytokine storms.
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High-throughput screening for antibody-based drugs
A collaboration between academia and industry has produced an assay and new screening technique which utilises directed evolution for the discovery of antibody-based drugs.
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Consortia of microbes could reduce inflammation and promote colon health, say researchers
A study has shown that two products of bacterial bile metabolism boost the conversion of precursor T cells into peripheral Tregs, which suppress chronic inflammation in the colon.
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Drug could prevent cognitive decline associated with brain tumour radiation
Researchers demonstrated NSPP completely prevented cognitive decline in mice treated with radiation for patient-derived glioblastomas.
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Stem cells in COPD patient lungs revealed as drug target for condition
There are heightened levels of abnormal stem cells in the lungs of COPD patients, presenting a drug target that researchers are screening compounds against.
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Celltrion selects 14 lead monoclonal antibodies for COVID-19 treatment
After screening 300 antibodies, Celltrion has identified the 14 most powerful that could potentially combat the COVID-19 coronavirus.
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The coronavirus as a personalised enemy of mankind
How has evolution led us to the point where humans are an ideal host for SARS-CoV-2, the virus that causes the COVID-19 coronavirus?
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Researchers reveal how remdesivir prevents COVID-19 viral replication
According to a new study, the drug remdesivir is a very potent inhibitor for coronavirus polymerases - demonstrating its potential for combatting COVID-19.
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COVID-19 Drug Repurposing Database made open-access by Excelra
The enterprise revealed that it has made its COVID-19 Drug Repurposing Database open-access to aid in the search for an effective therapeutic.
