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Cause of MS damage in the brain identified
A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.
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Research & Development
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Little progress shown for gender diversity in major pharma companies
A new report shows that there is still a lack of female representation within the senior roles of the major pharmaceutical companies.
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Gene differences that impact response to Cryptococcus identified
Using human data, a new study has examined how Cryptococcus genes impact patients with Cryptococcus Neoformans.
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Chemical synthesis and biological screening combined on chip
Researchers have developed a chip which facilitates and accelerates active substance production, characterisation and biological effectiveness.
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New potential liver cancer treatment found with biomarker-guided strategy
A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.
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Novel nanoparticles improve CRISPR gene editing
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
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Gene discovered to play key role in cancer metastasis
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
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RNA editing capabilities expanded with new CRISPR platform
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
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Macrophages identified as cause of endometriotic pain
Researchers have discovered that macrophages are a key cause for pain in women with endometriosis so could be a treatment target for the condition.
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Vaccine strategy devised to boost T-cell therapy
A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.
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Tauopathy-regulating protein identified
Researchers have discovered that the VPS35 molecule can be utilised in preventing neurodegenerative disorders.
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New evidence shows cytotoxic T cells can destroy targets of large mass
New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
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New target identified for vestibular diseases
Researchers have discovered a potential treatment for vestibular conditions such as dizziness in animal models.
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‘Longevity gene’ could be replicated to fight cardiovascular disease
The so-called 'longevity gene' has been included in animal models, in which it stopped atherosclerosis.
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Five latest developments for models
The use of models is a key feature of preclinical studies and in recent months there have been several new advancements in this area. This article investigates five of the latest developments.
