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Bone marrow stem cell transfusions show promise as potential treatment for sepsis
New research has shown that one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Engineered airway lining created to study how COVID-19 affects respiratory tracts
Researchers have made a respiratory model of COVID-19, made from patient-derived stem cells, to understand how the virus affects respiration and which could be used to test possible drugs.
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Model to study oculocutaneous albinism eye conditions developed
The first patient-derived stem cell model to research eye conditions related to oculocutaneous albinism (OCA) has been created.
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New model yields promising gene therapy for heart condition
Scientists in Japan have developed a credible heart cell model for arrhythmogenic cardiomyopathy and observed a positive response in the condition using PKP2 gene therapy.
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Whitepaper: How to successfully use iPSCs for disease modelling
Benefits and key considerations of using human iPSC-derived disease models in drug discovery.
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Organoid system simulates human liver-islet axis in diabetes
Scientists have developed a multi-organoid system from stem cells that can replicate the liver-islet axis in type 2 diabetes.
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Successful liver model developed for research into UCD
Urea cycle disorders affect the liver’s ability to excrete urea from the body. To test potential therapeutics requires an accurate model – a hurdle that has now been successfully navigated thanks to a team of researchers in Switzerland.
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Whitepaper: How to monitor and minimise off-target events
Whitepaper discusses strategies to optimize various factors that cause off-target events with Invitrogen™ TrueCut™ HiFi Cas9 Protein.
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Product hub: Introducing the latest addition to Thermo Fisher Scientific’s genome editing portfolio – InvitrogenTM TrueCutTM HiFi Cas9 Protein!
Read about the latest addition Invitrogen™ TrueCut™ HiFi Cas9 Protein to support your application and research goals.
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Under the microscope: Keying into UK biosciences – GenScript Biotech operations lands in Oxford
With operations in over 100 countries worldwide, GenScript Biotech, an industry leader in biotechnology reagent services, has established a new UK office in the Oxford area to better connect with the UK biosciences sector.
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Highlights from Drug Target Review’s Cell & Gene Therapy Advancements Online Summit
Here, we round up some of the key takeaways from the expert panel discussions at the Cell & Gene Therapy Advancements Online Summit.
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“Off-the-shelf” immunotherapies for cancer
In this article, Drug Target Review's Victoria Rees explores a new method that could enable powerful immune cells to be produced in large quantities to treat a range of cancers.
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Altered fat metabolism shown to play a key role in ALS
Scientists reveal that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis.
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Ncardia secures more than $60 million to enhance and expand leading iPSC offerings
Ncardia has formed a strategic partnership with Kiniciti to build GMP capabilities to support iPSC cell therapy platforms and human cell-based in vitro discovery services.
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Brochure: Biologics workflow solutions brochure
Biologics solutions from discovery to manufacturing.
