The carbon hydrogen functionalisation process could be used to make 3D scaffolds for pharmaceutical compounds, say researchers.
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Studies in mice have shown that the G-1 compound reduces obesity and the effects of diabetes by burning extra calories, report researchers.
Researchers have used a peptide called D6PV to lower triglycerides in mouse models, which could be used as a therapy for high triglyceride-induced acute pancreatitis in humans.
Modified sugar molecules have been developed by researchers as antiviral materials which are non-toxic to humans, according to a new study.
Mice given a novel drug that targets a key gene involved in lipid and glucose metabolism were able to tolerate a high-fat diet regimen without developing significant liver damage.
A study in mice has found that a compound modelled on a protein found in bananas safely protects against multiple strains of the influenza virus.
Researchers have screened thousands of existing drug molecules against cancer cell lines to discover almost 50 compounds that combat the condition.
Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
Researchers have discovered the most effective molecules to target DNA methylation from Plasmodium parasites, having shown success in pre-clinical trials.
PROTAC drugs that safely and effectively target leukaemia and lymphoma cells have been developed by researchers.
The ICR has revealed that during drug discovery, researchers should not use general search engines and vendor catalogue information to decide on their use of chemical probes.
A new study into the molecular causes of acute lymphoblastic leukaemia could lead to a new target for therapy.
Molecular drivers of Parkinson's disease have been revealed by scientists who also determined how they impact the functions of genes involved in the condition and the results may point to potential new treatments.
Molecules made by immune cells to transport sodium lactate could be a target for treatment to stop the lactate build-up in chronic inflammatory disorders.
A microRNA inhibitor has been identified which reduced the sizes of aggressive CNS tumours and improved survival in mice.