List view / Grid view

Articles

Drug Target Review – Issue #4 2016

11 December 2016 | By Drug Target Review

Included in this issue: Profiling proteins produced by cells to provide information about cell signalling pathways; HTS assays for the identification of small-molecule inhibitors of deubiquitinating enzymes; Preventing the spread of infectious diseases in transport hubs...

Valid biomarker signatures from liquid biopsies – how to standardise NGS

6 December 2016 | By , ,

The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…

How artificial intelligence is the future of pharma

5 December 2016 | By Professor Jackie Hunter, BenevolentBio

Artificial Intelligence and machine learning present the industry with a real opportunity to do R&D differently, writes BenevolentBio's Jackie Hunter...

HTS assays for the identification of small-molecule inhibitors of deubiquitinating enzymes

4 December 2016 | By , ,

The covalent modification of proteins by the attachment of ubiquitin (ubiquitination) is best known for its function to label proteins for proteasomal degradation. However, ubiquitination also plays non-proteasomal roles during signal transduction, DNA repair and protein sorting...

D is for Diabetes

17 November 2016 | By Niamh Louise Marriott, Digital Content Producer

D is for Diabetes - the next instalment of our daily pharmaceutical alphabet bringing you up to date with all the latest news and research into Diabetes...

C is for CRISPR

16 November 2016 | By Niamh Louise Marriott, Digital Content Producer

C is for CRISPR - the next instalment of our daily pharmaceutical alphabet bringing you up to date with all the latest news and research of CRISPR technology

B is for Biomarkers

15 November 2016 | By Niamh Louise Marriott, Digital Content Producer

B is for Biomarkers - the next instalment of our daily pharmaceutical alphabet bringing you up to date with all the latest news and research on the subject of biomarkers.

A is for Alzheimer’s disease

14 November 2016 | By Niamh Louise Marriott, Digital Content Producer

A is for Alzheimer's - the first instalment of our daily pharmaceutical alphabet bringing you up to date with all the latest news and research on the fight against this deadly disease

IVF babies: Easy as 1, 2…3?

3 November 2016 | By Niamh Louise Marriott, Digital Content Producer

The ethics of three parent babies has been widely debated - should it be used to save children from deadly mitochondrial diseases or are scientists "playing God"? Here's everything you need to know to decide...

Rural, poor and sick: The unseen cancer crisis in America

20 October 2016 | By Aaron Yao, PhD, University of Virginia School of Medicine

PhD student Aaron Yao highlights the shocking disparities between rural and urban eastern America and how the odds of cancer survival do not favour the impoverished...