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Alzheimer’s disease

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New gene therapy repairs neuron stroke damage in mice

12 September 2019 | By Victoria Rees (Drug Target Review)

Researchers have developed a new treatment method which turned glial cells into functioning neurons in mice after stroke.

news

Compound promotes healing of myelin in nervous system disorders

6 September 2019 | By Rachael Harper (Drug Target Review)

A compound that promotes the rebuilding of the protective sheath around nerve cells damaged in multiple sclerosis has been developed.

news

Scientists identify promising new target to combat Alzheimer’s disease

4 September 2019 | By Rachael Harper (Drug Target Review)

New research is the first to link maladaptive changes in calcium transport by mitochondria to the progression of Alzheimer's disease.

news

Gene linked to rare disorder also regulates key enzyme in Alzheimer’s

22 August 2019 | By Rachael Harper (Drug Target Review)

A gene associated with a rare balance disorder also regulates the behaviour of an enzyme that increases the risk for Alzheimer's disease.

news

Link between immune cells and Alzheimer’s discovered

21 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have found that the presence of microglia brain cells allowed plaques to form in the brains of rodents, leading to Alzheimer’s disease.

news

Genes linked to Alzheimer’s risk have been identified

15 August 2019 | By Nic Losardo (Drug Target Review)

Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.

news

Direct toxic action of beta-amyloid in Alzheimer’s patients identified

12 August 2019 | By Rachael Harper (Drug Target Review)

The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.

news

New model predicts cognitive decline two years ahead

6 August 2019 | By Rachael Harper (Drug Target Review)

Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.

news

Tauopathy-regulating protein identified

11 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered that the VPS35 molecule can be utilised in preventing neurodegenerative disorders.

news

Potential new therapeutic target for Alzheimer’s discovered

18 June 2019 | By Drug Target Review

New study finds a promising antagonist that blocks specific interaction between the protein apoE and amyloid precursor protein.

news

Alzheimer’s protein found, suggesting new drug target

13 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have found a new drug target for Alzheimer’s disease after identifying a facilitating protein.

news

Researchers take a leap forward for new anti-inflammatory drugs

13 May 2019 | By Drug Target Review

Treatments for chronic inflammatory diseases are one step closer as a new study discovers a way to stop inflammation in its tracks.

news

New technology to produce dorsal cortical neurons using iPS

1 April 2019 | By Drug Target Review

Scientists expect that it will soon be possible to treat brain diseases by restoring damaged areas in the brain by mass producing neurons using stem cells...

news

Bacterial pathogens found in brains of Alzheimer’s patients

24 January 2019 | By Drug Target Review

Researchers have found bacterial pathogens in the brains of Alzheimer's patients, and have shown that they could be driving progression of the disease...

news

‘Hidden pocket’ could be targeted to treat strokes

21 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...

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Alzheimer’s disease